Gap Junctions in the Brain

Physiological and Pathological Roles

By: Ekrem Dere

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Hardcover | 30 August 2012 | Edition Number 1

At a Glance

Hardcover
304 Pages

Dimensions(cm)
25.4 x 21.59 x 2.54

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Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.

Serves as the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain
Chapters summarize knowledge of the basic physiology of gap junctions in the brain, as well as of human disease conditions associated with mutations in single gap junction connexin genes
Includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants

Industry Reviews

"Dere.introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction- related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases."--Reference and Research Book News, February 2013

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You Can Find This Book In

Non-Fiction Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Other Branches of Medicine Psychiatry Science Biology, Life Sciences Life Sciences in General Neurosciences Pathology

Physiology of gap junctions in the brain
Gap junctions between astrocytes, neurons, and glia-neuron interactions
The role of gap junctions in brain development, neurogenesis and synaptic plasticity
Gap junctions and neuronal synchronization
Gap junctions and neurological and neuropsychiatric diseases
Gap junctions and behavior
Table of Contents provided by Publisher. All Rights Reserved.

Gap Junctions in the Brain

Physiological and Pathological Roles

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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