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Metabotropic Gpcrs : Tgr5 and P2y Receptors in Health and Diseases - Senthilkumar Rajagopal

Metabotropic Gpcrs

Tgr5 and P2y Receptors in Health and Diseases

By: Senthilkumar Rajagopal, Murugavel Ponnusamy

Hardcover | 27 November 2018

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Module 1_ Overview of G-Protein coupled receptor.- Chapter 1. General Introduction.- Chapter 2. General Classification.- Chapter 3. Role of GPCR receptors - In development and Physiology.- Chapter 4. Metabotropic Receptors - Sub family and Distribution.- Module 2_ TGR5 receptor.- Chapter 5. Introduction.- Chapter 6. Plasma Membrane receptors [TGR5].- Chapter 7. Nuclear Membrane receptors [FXR].- Chapter 8. Gene expression and signaling pathways of TGR5 receptors.- Chapter 9. Physiological and pathological role of TGR5 receptors.- Chapter 10. Summary.- Module 3_ P2Y receptor.- Chapter 11. Introduction.- Chapter 12. P2Y receptor expression and Regulation.- Chapter 13. Signaling Pathways of P2Y receptors.- Chapter 14. Physiological Role of P2Y.- Chapter 15. P2Y in pathophysiology (Renal, Lungs, Cardiovascular system, Brain, etc).- Chapter 16. Summary.- Module 4_ Therapeutically Targeting TGR5 & P2Y receptors.- Chapter 17. Introduction.- Chapter 18. Agonist and Antagonists of TGR5 & P2Y receptors.- Chapter 19. Pharmacological agents targeting TGR5 and its clinical benefits.- Chapter 20. Pharmacological Agents Targeting P2Y receptors and its clinical benefits.- Chapter 21. Conclusive Summary and Future Perspectives.

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