Dendritic Cells

Biology and Clinical Applications

By: Michael T. Lotze, Angus W. Thomson

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Hardcover | 20 August 2001 | Edition Number 2

At a Glance

Hardcover
794 Pages

Edition Type
Revised

Dimensions(cm)
26.04 x 20.96 x 4.45

Hardcover

RRP $504.95

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Dendritic Cells, Second Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry.

An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on:

Imaging
Interaction of dendritic cells with viruses
Dendritic cells and dendrikines, chemokines and the endothelium
Molecules expressed in dendritic cells
Role of dendritic cells in wound healing and atherosclerosis
Delivery of apoptotic bodies
Genetic engineering of dendritic cells
Imaging
Practical aspects of clinical protocol development

Industry Reviews

"This is an excellent book that will serve as a valuable source of information for many researchers both in and outside the field of dendritic cell biology. The scope and range of information in this book make it a significant contribution to the scientific literature. The fact that this second edition was published only three years after the first edition speaks to the importance and vitality of the dendritic cell biology field." Alvin Telser for DOODY'S (2003) Praise for the First Edition "...represents the first book that attempts to draw together the exponential growth in our knowledge about this fundamental cell." -IMMUNOLOGY TODAY (March 2000)

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Science Biology, Life Sciences Cellular Biology Infectious & Contagious Diseases Nursing & Ancillary Services Nursing Molecular Biology

Contributors	p. ix
Foreword to the Second Edition	p. xv
Preface to the Second edition	p. xviii
Preface to the First Edition	p. xxi
Origin and Molecular Biology of Dendritic Cells	p. 1
The Development of Dendritic Cells from Hematopoietic Precursors	p. 3
Dendritic Cells in the Thymus	p. 13
T-cell Activation and Polarization by Dendritic Cells	p. 21
Follicular Dendritic Cells: Molecules Associated with Function	p. 29
Langerhans Cells	p. 35
Dendritic Cell-Related Immunoregulation: Signals and Mediators	p. 51
Dendritic Cell Biology	p. 75
Isolation, Culture and Propagation of Dendritic Cells	p. 77
Phenotypic Characterization of Dendritic Cells	p. 97
Targeted Knockouts Affecting DCs	p. 119
Mobilization, Migration, and Localization of Dendritic Cells	p. 131
Regulation of Antigen Capture, MHC Biosynthesis and Degradation by Dendritic Cells	p. 151
Development and Testing of Dendritic Cell Lines	p. 165
Dendritic Cell-Derived Exosomes	p. 179
Dendritic Cells as Recipients of Cytokine Singals	p. 187
Dendritic Cells and Chemokines	p. 203
Studies of Endocytosis	p. 213
Imaging Dendritic Cells: a Primer	p. 231
Dendritic Cells and Interaction with other Cells	p. 243
NK Cells	p. 245
B cells	p. 255
Cells of the Monocyte/Macrophage Lineage	p. 263
Endothelium	p. 275
Dendritic Cell/Dendritic Cell Interaction	p. 289
Dendritic cells in the Periphery	p. 299
Dendritic Cells in the Context of Skin Immunity	p. 301
Dendritic Cells in the Respiratory Tract	p. 315
Intestinal Dendritic Cells	p. 325
Dendritic Cells in the Liver, Kidney, Heart, and Pancreas	p. 337
Dendritic Cells in the Spleen and Lymph Nodes	p. 357
Dendritic Cells in the Central Nervous System	p. 371
Dendritic Cells in the Eye	p. 389
Dendritic Cells in the Reproductive Tract	p. 411
Dendritic Cells in Disease	p. 423
The Identification of dendritic cells in cancer	p. 425
Dendritic Cells in Rejection and Acceptance of Solid Organ Allografts	p. 439
Dendritic Cells and Autoimmunity	p. 459
Interaction of Dendritic Cells with Bacteria	p. 473
Dendritic Cells During Infection with HIV-1 and SIV	p. 487
Interactions of Viruses with Dendritric Cells	p. 505
Dendritic Cells in Allergy	p. 523
DCs in Wound Healing	p. 539
Dendritic Cells in Atherosclerosis	p. 547
DC-Based Therapies	p. 559
Clinical Trials of Dendritic Cells for Cancer	p. 561
Dendritic Cell Therapies for HIV-1 Infection	p. 573
Dendritic Cell Tolerogenicity and Prospects for Dendritic Cell-Based Therapy of Allograft Rejection and Autoimmune disease	p. 587
Genetic Engineering of Dendritic Cells	p. 609
Phagocytosis of Apoptotic Cells	p. 627
Dendritic Cells and the Biology of Parasitism	p. 645
Annotated References by Year	p. 651
Index	p. 771
Table of Contents provided by Syndetics. All Rights Reserved.

Dendritic Cells

Biology and Clinical Applications

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

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