
The Great Nerve
The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes
By: Kevin Tracey
Paperback | 19 August 2025 | Edition Number 1
At a Glance
Paperback
23.2 x 15.3 x 3.2
Paperback
RRP $36.99
$29.75
20%OFF
or 4 interest-free payments of $7.44 with
Your health and happiness depend on a bundle of 200,000 nerve fibres that hold the secrets to life itself
The vagus nerve is often referred to as the 'superhighway' which connects every organ of the body to the brain, and vice versa, but it is so much more than just traffic.
The 'great nerve' vibrates in tune with your health like the instruments of an orchestra- when your vagus nerve is healthy, so are you. When it isn't, you experience everything from poor sleep to low mood, pain, suffering and chronic illness.
Recent scientific developments, including Dr Kevin Tracey's research showing how the vagus nerve is linked to the immune system, have brought the nerve to the attention of everyone from neuroscientists to TikTok influencers.
In The Great Nerve Dr Tracey shares the science of how the vagus nerve operates to regulate our health, how we can help it, and the truth behind popular 'vagus nerve stimulating' strategies such as ice baths, meditation, exercise and breathwork.
He reveals the extraordinary new science that promises to revolutionise healthcare, where computer chips may regulate your blood sugar, and electrical implants may replace your medications forever.
Trailblazing vagus nerve stimulation therapy is demonstrating potential to reverse life-altering diseases like rheumatoid arthritis, inflammatory bowel disease, lupus, multiple sclerosis, diabetes, obesity, stroke, depression, Alzheimer's and Parkinson's.
The Great Nerve not only revolutionises how we will understand and treat disease, it gives us unprecedented hope for our health.
Dr Kevin Tracey is a neurosurgeon, scientist, entrepreneur, and leader in the fields of inflammation and vagus nerve stimulation. Along with his colleagues in his lab at the Feinstein Institutes, Dr. Tracey discovered the molecular and neural mechanism for the reflexive control of inflammation, now termed the inflammatory reflex. He is a prolific inventor with more than 120 U.S. patents. As measured by and reported in the scientific journal PLOS One, Dr. Tracey is one of the most highly cited living scientists in the world.
Industry Reviews
The Great Nerve is a game changer. Dr Tracey connects cutting-edge science to real world health, showing how the vagus nerve can harmonise our gut microbes, optimise our immune system, and reduce inflammation. Grab this book today and learn how the connection between your brain, gut and immune system can transform your health -- Will Bulsiewicz, MD MSCI, New York Times bestselling author of Fiber Fueled
The Great Nerve is an extraordinary journey into how modern medicine is innovating the way we treat chronic illness and autoimmune disorders. This is a groundbreaking, hopeful look at how vagus nerve stimulation will reshape medical treatments in the future -- Terry Wahls, MD, author of The Wahls Protocol
Dr Tracey's The Great Nerve is so fascinating that no reader will ever forget it, and for many the book will be lifesaving. The book is an easily understood operator's manual for the very core of our being, the vagus nerve, full of examples from transformed patients' lives and how-to guidance for the reader. After reading, I have no doubt that my body and my vagus nerve are synchronistic, and I know just what to do to help each help the other -- Martine Rothblatt, PhD, inventor, creator of SiriusXM, and CEO of United Therapeutics Corp
Did you know that your brain can control your immune system? Neither did most doctors and scientists, until recently. In The Great Nerve, Kevin Tracey describes the science and medicine of the vagus nerve through a kaleidoscope of medical history, patient stories, accidental discoveries, and careful investigation. Readable, personal, and enthusiastic, this book brings Tracey's passion and style to a broad audience -- Cori Bargmann PhD, neurobiologist
The Great Nerve, a remarkable book, reveals the untapped potential of the vagus nerve to change the way we approach health and disease. Through vivid case studies, Dr Tracey, a pioneer in this field, demonstrates how vagus nerve stimulation has the power to treat inflammation and dramatically change lives by unlocking a patient's innate ability to heal. He even shows how this is true in rheumatoid arthritis patients resistant to drugs, introducing an exciting future for medical treatment -- Sir Marc Feldmann FRS, immunologist and Lasker Prize Award Winner
ISBN: 9780241762417
ISBN-10: 0241762413
Published: 19th August 2025
Format: Paperback
Language: English
Audience: General Adult
Publisher: Penguin UK
Country of Publication: GB
Edition Number: 1
Dimensions (cm): 23.2 x 15.3 x 3.2
Weight (kg): 0.39
Shipping
| Standard Shipping | Express Shipping | |
|---|---|---|
| Metro postcodes: | $9.99 | $14.95 |
| Regional postcodes: | $9.99 | $14.95 |
| Rural postcodes: | $9.99 | $14.95 |
Orders over $0.00 qualify for free shipping.
How to return your order
At Booktopia, we offer hassle-free returns in accordance with our returns policy. If you wish to return an item, please get in touch with Booktopia Customer Care.
Additional postage charges may be applicable.
Defective items
If there is a problem with any of the items received for your order then the Booktopia Customer Care team is ready to assist you.
For more info please visit our Help Centre.
You Can Find This Book In

Hormone Havoc
A Science-Backed Protocol for Perimenopause and Menopause: Sleep Better. Think Better. Feel Better.
Paperback
RRP $34.99
$28.75
OFF

The New Perimenopause
An Evidence-Based Guide to Surviving the Zone of Chaos and Feeling Like Yourself Again
Paperback
RRP $36.99
$25.61
OFF

The Menopause Brain
The new science for women to navigate midlife and optimise brain health for later years
Paperback
RRP $34.99
$28.75
OFF

The Power of Hormones
Break free from fear and misinformation about hormones and harness them for a healthier, happier life
Paperback
RRP $34.99
$28.75
OFF

Age Like a Girl
How Menopause Rewires Your Brain for Mental Clarity, Increased Confidence, and Renewed Energy
Paperback
RRP $36.99
$22.99
OFF



















