| Keynote Presentation | |
| Expanding the Circle 1975-1999: Sulfur Biochemistry and Insights on the Biological Functions of Taurine | p. 1 |
| Appreciations | |
| Emeritus Professor Doriano Cavallini: A Life for Sulfur Biochemistry | p. 27 |
| Emeritus Professor Alberto Giotti: A Father of Taurine Research | p. 31 |
| Plenary Presentations | |
| Mode of Action of Taurine and Regulation Dynamics of Its Synthesis in the CNS | p. 35 |
| Taurine and Skeletal Muscle Ion Channels | p. 45 |
| Taurine-deficient Cardiomyopathy: Role of Phospholipids, Calcium, and Osmotic Stress | p. 57 |
| Basic Aspects and Peripheral Actions of Taurine | |
| Post-transcriptional Regulation of Cysteine Dioxygenase in Rat Liver | p. 71 |
| The Mitochondrial Permeability Transition and Taurine | p. 87 |
| Cloning and Characterization of the Promoter Region of the Rat Taurine Transporter (TauT) Gene | p. 97 |
| Taurine Prevents Ischemia Damage in Cultured Neonatal Rat Cardiomyocytes | p. 109 |
| Effects of Taurine and Thiosulfate on the Spectrophotometric Properties of RNA and DNA | p. 117 |
| Ionomycin Restores Taurine Transporter Activity in Cyclosporin-A Treated Macrophages | p. 127 |
| Metabolic and Nutritional Aspects | |
| Daily Dietary Taurine Intake in Japan | p. 137 |
| Comparative Studies on Serum Taurine and Plasma Fatty Acids in Humans between the Sea Side Area in Toyama, Japan and the Mountain Areas in Inner Mongolia, China | p. 143 |
| Biochemical and Ultrastructural Alterations in Rat after Hyperoxic Treatment: Effect of Taurine and Hypotaurine | p. 149 |
| Hypotaurine Protection on Cell Damage by Singlet Oxygen | p. 157 |
| Hypotaurine and Superoxide Dismutase: Protection of the Enzyme against Inactivation by Hydrogen Peroxide and Peroxidation to Taurine | p. 163 |
| Dietary Taurine Changes Ascorbic Acid Metabolism and Cholesterol Metabolism in Rats Fed Diets Containing Polychlorinated Biphenyls | p. 169 |
| Effects of Long-term Treatment with Taurine in Mice Fed a High-fat Diet: Improvement in Cholesterol Metabolism and Vascular Lipid Accumulation by Taurine | p. 177 |
| Hypolipidemic Effect of Taurine in Golden Syrian Hamsters | p. 187 |
| Taurine Reduces Atherosclerotic Lesion Development in Apolipoprotein E-deficient Mice | p. 193 |
| Does Taurine Play an Osmolarity Role during Ethanol Intoxication? | p. 203 |
| Taurine in the CNS | |
| Osmotic Sensitivity of Taurine Release from Hippocampal Neuronal and Glial Cells | p. 213 |
| Isovolumic Regulation in Nervous Tissue: A Novel Mechanism of Cell Volume Regulation | p. 219 |
| New Role of Taurine as an Osmomediator between Glial Cells and Neurons in the Rat Supraoptic Nucleus | p. 227 |
| Gene Expression of Taurine Transporter and Taurine Biosynthetic Enzymes in Hyperosmotic States: A Comparative Study with the Expression of the Genes Involved in the Accumulation of Other Osmolytes | p. 239 |
| Involvement of Ion Channels in Ischemia-induced Taurine Release in the Mouse Hippocampus | p. 249 |
| Modulation of Taurine Release by Metabotropic Receptors in the Developing Hippocampus | p. 257 |
| Extracellular Taurine as a Parameter to Monitor Cerebral Insults 'On-Line': Time Courses and Mechanisms as Studied in Vivo | p. 265 |
| Effects of Taurine and Some Structurally Related Analogues on the Central Mechanism of Thermoregulation: A Structure-Activity Relationship Study | p. 273 |
| Taurine-induced Synaptic Potentiation: Dependence on Extra- and Intracellular Calcium Sources | p. 283 |
| The Effect of Kainic Acid and AMPA on the Release of Taurine and GABA from the Rat Substantia Nigra in Vivo | p. 293 |
| Effects of Ethanol and Glutamate Agonist Infusion on the Outflow of Sulphoacetaldehyde: Microdialysis Studies | p. 297 |
| Taurine, Glutamine, Glutamate, and Aspartate Content and Efflux, and Cell Volume of Cerebrocortical Minislices of Rats with Hepatic Encephalopathy: Influence of Ammonia | p. 305 |
| The Effect of Taurine Derivative on Lipid Peroxidation and Interhemispheric Asymmetry of Phospholipids from the Brain Synaptosomes in Rats after Immobilization Stress | p. 313 |
| Taurine Transport Mechanism through the Blood Brain Barrier in Spontaneously Hypertensive Rats | p. 321 |
| Protection of Intrinsic Nerves of Guinea-Pig Detrusor Strips against Anoxia/Glucopenia and Reperfusion Injury by Taurine | p. 325 |
| The Possible Role of Taurine and GABA as Endogenous Cryogens in the Rabbit: Changes in CSF levels in Heat-Stress | p. 335 |
| Taurine Analogues and Metals: Health Care Aspects (Supported by COST D8 and D13) | |
| Interaction of Taurine with Metal Ions | p. 345 |
| Attenuation of Oxidative Damage to DNA by Taurine and Taurine Analogs | p. 355 |
| Tyrosine-Hydroxylase Immuno-reactive Cells in the Rat Striatum following Treatment with MPP[superscript +] | p. 369 |
| Investigation of the Therapeutic Efficacy of a Taurine Analogue during the Initial Stages of Ethanol Detoxification: Preliminary Studies in Chronic Alcohol Abusers | p. 375 |
| Metabolism of Taurine to Sulphoacetaldehyde during Oxidative Stress | p. 383 |
| Taurine Chloramine Attenuates the Hydrolytic Activity of Matrix Metalloproteinase-9 in LPS-activated Murine Peritoneal Macrophages | p. 389 |
| Synthesis of Taurine Analogues from Alkenes: Preparation of 2-Aminocycloalkanesulfonic Acids | p. 399 |
| Effects of Guandinoethane Sulfonate on Contraction of Skeletal Muscle | p. 403 |
| Protection by Taurine and Structurally Related Sulfur-containing Compounds against Erythrocyte Membrane Damage by Hydrogen Peroxide | p. 411 |
| Taurine and Vision | |
| Regulation of High Affinity Taurine Transport in Goldfish and Rat Retinal Cells | p. 431 |
| Effects of Osmotic and Light Stimulation on [superscript 3]H-Taurine Efflux from Isolated Rod Outer Segments and Synthesis of Tauret in the Frog Retina | p. 441 |
| New HPLC Evidence on Endogenous Tauret in Retina and Pigment Epithelium | p. 453 |
| Characterization of Taurine Uptake in the Rat Retina | p. 461 |
| Calcium Uptake in the Rat Retina is Dependent on the Function of the Cyclic Nucleotide-gated Channel: Pharmacologic Evidence | p. 469 |
| Effects of Calmodulin Antagonists on Taurine-stimulated Calcium Ion Uptake in the Rat Retina are Partly Independent of Calmodulin Activity | p. 477 |
| Taurine and Cell Homeostatic Mechanisms | |
| Swelling-induced Taurine Efflux from HeLa Cells: Cell Volume Regulation | p. 487 |
| Taurine Fluxes in Insulin Dependent Diabetes Mellitus and Rehydration in Streptozotocin Treated Rats | p. 497 |
| In Vitro and in Vivo Effects of Taurine and Structurally Related Sulfur-containing Compounds against Phenylhydrazine-induced Oxidative Damage to Erythrocytes | p. 503 |
| A Taurine Transporter Isolated from Rat Cardiac Muscle | p. 523 |
| Identification of Promoter Elements Involved in Adaptive Regulation of the Taurine Transporter Gene: Role of Cytosolic Ca[superscript 2+] Signaling | p. 535 |
| Suppression of Bleomycin-induced Increased Production of Nitric Oxide and NF-[kappa]B Activation by Treatment with Taurine and Niacin | p. 545 |
| Cytoprotective Effect of Taurine against Hypochlorous Acid Toxicity to PC12 Cells | p. 563 |
| Effect of Taurine and [beta]-Alanine on Morphological Changes of Pancreas in Streptozotocin-induced Rats | p. 571 |
| Immunohistochemical Localization of Insulin in Pancreatic [beta]-Cells of Taurine-supplemented or Taurine-depleted Diabetic Rats | p. 579 |
| Taurine Attenuates the Induction of Immediate-Early Gene Expression by PDGF-BB | p. 589 |
| Clinical Aspects | |
| Post-operative Monitoring of Cortical Taurine in Patients with Subarachnoid Hemorrhage: A Microdialysis Study | p. 595 |
| Taurine Intake and Excretion in Patients Undergoing Long Term Enteral Nutrition | p. 605 |
| Does the Taurine Transporter Gene Play a Role in 3P-Syndrome? | p. 613 |
| Extracellular Levels of Taurine in Tumoral, Peritumoral, and Normal Brain Tissue in Patients with Malignant Glioma: An Intraoperative Microdialysis Study | p. 621 |
| The Treatment of Ammonia Poisoning by Taurine in Combination with a Broncholytic Drug | p. 627 |
| Concluding Comments | p. 631 |
| Appendix | |
| Some Taurine Analogues Referred to in This Book | p. 633 |
| Index | p. 639 |
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