Reconceiving the Gene

Seymour Benzer's Adventures in Phage Genetics

By: Frederic Lawrence Holmes, William C. Summers (Editor)

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Hardcover | 1 June 2006 | Edition Number 1

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Hardcover
352 Pages

Dimensions(cm)
2.42 x 1.85 x 0.29

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This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age.

Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.

Industry Reviews

"Holmes, a master of the historical fine-mapping of science, uses Benzer's pathbreaking contributions to show how molecular biology and classical genetics converged in the mid-twentieth century."-Angela Creager, Princeton University

-- Angela Creager

"Famous for his exploration of the investigative pathways by which scientists have arrived at major discoveries, the late Professor Holmes has here applied this approach to Benzer's study of the fine structure of the genetic map of a bacterial virus. Scholarly, authoritative and a revelation."-Robert Olby, University of Pittsburgh

-- Robert Olby

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Life Sciences in General Genetics excluding Medical Molecular Biology Science in General History of Science Biographies & True Stories Biographies Chemistry Medicine

Pre-Clinical Medicine & Basic Sciences Medical Genetics

Preface	p. vii
Acknowledgments	p. xi
Author's Note	p. xiii
Classical Mendelian Genetics	p. 1
Genetics and the Phage Biologists	p. 29
The Physicist Becomes a Phage Biologist	p. 75
To Paris and Back	p. 122
Teaching and Research at Purdue	p. 146
Entering the rII Region	p. 179
Crossing into the Fine Structure	p. 222
Is Gene a Dirty Word?	p. 269
The Survival of the "Gene"	p. 299
Notes	p. 303
Index	p. 331
Table of Contents provided by Ingram. All Rights Reserved.

Reconceiving the Gene

Seymour Benzer's Adventures in Phage Genetics

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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