This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.
..."this first-rate volume does a commendable job in summarizing, in a clear, lucid, and understandable manner, the current knowledge in the field of proteoglycans. The editor and the 31 authors of this excellent volume deserve congratulations....chapters cover all major proteoglycans with clear and up-to-date information on their chemical structure, biosynthesis, catabolism, interactions with the extracellular matrix, cell membranes, cytokines, and the myriad of biologic functions possessed by these fascinating molecules. There are abundant diagrams that help clarify points and solidify information.... ...enthusiastically recommended, not only to those interested in proteoglycans, but also to all concerned with the extracellular matrix and cell biology. In particular it would be helpful to pathologists and may, perhaps, help to stamp out the old term mucosubstances." ---Modern Pathology, 2000