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Proteoglycans : Structure, Biology And Molecular Interactions - Renato V. Iozzo


Structure, Biology And Molecular Interactions

By: Renato V. Iozzo (Editor)

Paperback Published: 5th April 2000
ISBN: 9780824703349
Number Of Pages: 442

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This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.

Industry Reviews

..."this first-rate volume does a commendable job in summarizing, in a clear, lucid, and understandable manner, the current knowledge in the field of proteoglycans. The editor and the 31 authors of this excellent volume deserve congratulations....chapters cover all major proteoglycans with clear and up-to-date information on their chemical structure, biosynthesis, catabolism, interactions with the extracellular matrix, cell membranes, cytokines, and the myriad of biologic functions possessed by these fascinating molecules. There are abundant diagrams that help clarify points and solidify information.... ...enthusiastically recommended, not only to those interested in proteoglycans, but also to all concerned with the extracellular matrix and cell biology. In particular it would be helpful to pathologists and may, perhaps, help to stamp out the old term mucosubstances." ---Modern Pathology, 2000

Prefacep. iii
Contributorsp. vii
Introductory Remarks and Overviewp. 1
Structure and Biosynthesis of Chondroitin Sulfate and Hyaluronanp. 5
Heparan Sulfate: Molecular Structure and Interactions with Growth Factors and Morphogensp. 27
Hyaluronanp. 61
Catabolism of Proteoglycansp. 93
Syndecansp. 115
Signaling Through the Syndecan Proteoglycansp. 147
Glypicansp. 161
Serglycin Proteoglycans: The Family of Proteoglycans Stored in the Secretory Granules of Certain Effector Cells of the Immune Systemp. 177
Small Leucine-Rich Proteoglycansp. 201
Corneal Proteoglycansp. 237
Heparan Sulfate Proteoglycans in Basement Membranes: Perlecan, Agrin, and Collagen XVIIIp. 275
Versicanp. 327
Aggrecanp. 343
Chrondroitin Sulfate Proteoglycans in the Nervous Systemp. 379
Indexp. 403
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780824703349
ISBN-10: 0824703340
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 442
Published: 5th April 2000
Country of Publication: US
Dimensions (cm): 23.5 x 16.51  x 2.54
Weight (kg): 0.72
Edition Number: 1

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