Integrated Neuroscience

A Clinical Problem Solving Approach

By: Elliott M. Marcus, Stanley Jacobson

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Hardcover | 30 November 2002 | Edition Number 1

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756 Pages

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INTEGRATED NEUROSCIENCES This textbook takes as a premise that, in order to make intelligent diagnosis and provide a rational treatment in disorders of the nervous system, it is necessary to develop the capacity to answer the basic questions of clinical neurology: (1) Where is the disease process located? (2) What is the nature of the disease process? The purpose of this textbook is to enable the medical student to acquire the basic information of the neurosciences and neurology and most importantly the ability to apply that information to the solution of clinical problems. The authors also suggest that hospital trips be a part of any Clinical Neurosciences Course so that the student can put into actual practice what he has learned in the classroom. We believe that this textbook will be of value to the student throughout the four years of the medical school curriculum. Medical, psychiatry and neurology residents may also find this text of value as an introduction or review. It is more true in neurology than in any other system of medicine that a firm knowledge of basic science material, that is, the anatomy, physiology and pathology of the nervous system, enables the student and physician to readily arrive at the diagnosis of where the disease process is located and the nature of the most likely pathology. Subsequently that knowledge may be applied to problem solving in clinical situations.

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Non-Fiction Science Biology, Life Sciences Life Sciences in General Neurosciences Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology

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Published: 1st November 2012

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Preface
Dedication
Introduction to Basic Neurobiology
Overview of the nervous system	p. 21
The neuron	p. 1
The central nervous system	p. 3
Spinal Cord	p. 3
Brain Stem	p. 4
Diencephalon	p. 6
Cerebrum	p. 8
CNS pathways	p. 14
Glands associated with the brain	p. 17
Blood supply	p. 17
Meninges	p. 18
Ventricular system	p. 19
Overview of localization of function and neurological diagnosis	p. 28
Where is the disease located? What is the nature of the pathology?	p. 1
The neurological history and examination	p. 8
Diagnostic studies in Neurology	p. 11
Neurocytology	p. 31
Neurons	p. 1
Myelin	p. 8
Axoplasmic flow	p. 10
Synapse	p. 14
Supporting Cells of the Central Nervous System	p. 20
Response of Nervous system to Injury	p. 24
Degeneration	p. 24
Regeneration	p. 26
Neuroembryology	p. 23
Introduction	p. 1
Histogenesis	p. 2
Neuronal Necrosis and apoptosis	p. 4
Differentiation of CNS areas Ventricular System	p. 5
Spinal Cord	p. 5
Brain	p. 7
Cranial Nerves	p. 10
Cerebral cortex	p. 13
Abnormal development	p. 16
Basic Physiology	p. 28
Cell physiology	p. 1
Cell Membrane	p. 1
Channels	p. 2
Potassium Channels	p. 5
Nerve Physiology	p. 11
Action Potential	p. 10
Sodium Channels	p. 11
Saltatory Conduction	p. 15
Calcium channels	p. 17
Regional Approach to Neuroanatomy and Localization
Skeletal Muscle and Nerve-Muscle Junction	p. 25
Gross Structure and function	p. 1
Molecular Architecture of Contraction	p. 5
Nerve Muscle Junction	p. 9
Disease of Muscle	p. 12
Muscular Dystrophies	p. 12
Myotonic Dystrophy
Congenital Myopathies	p. 16
Acquired Disorders of Muscle	p. 18
Disease of the Neuromuscular Junction	p. 19
Spinal Cord: Structure and Physiology	p. 27
Anatomy	p. 1
Segmental functions	p. 4
Reflexes	p. 6
Membrane basis of integration	p. 9
Stretch receptors	p. 12
Lamination in spinal cord gray matter	p. 17
Nociception and pain	p. 19
Tracts	p. 22
Descending	p. 23
Ascending	p. 23
Disease of Peripheral Nerve and Nerve Root	p. 25
Introduction	p. 1
Mononeuropathies	p. 4
Polyneuropathies	p. 15
Radiculopathies	p. 19
Clinical Considerations of the Spinal Cord	p. 29
Spinal cord compression and transection syndromes	p. 1
Extrinsic disorders	p. 3
Intrinsic diseases
Segmental	p. 10
System	p. 17
Multifocal	p. 17
Case History Problem Solving Part I: Spinal Cord, Nerve Root	p. 9
Lesion Diagrams	p. 1
Case Histories	p. 2
Functional Anatomy of the Brain Stem	p. 33
Introduction	p. 1
Functional Localization in Coronal Sections of the brain stem	p. 2
Functional Centers in the Brain Stem	p. 20
Localization of Disease Processed in the Brain Stem	p. 25
Brain Stem and Eye Movements	p. 30
Cranial Nerves	p. 25
Components	p. 1
Function of each cranial nerve	p. 23
Effects of Extrinsic Lesions on Cranial Nerves	p. 23
Voluntary Control of the Cranial Nerves	p. 23
Brain Stem: Clinical Considerations	p. 21
Differentiation of extrinsic and intrinsic lesions
Extrinsic disorders	p. 2
Intrinsic disorders	p. 8
Vascular	p. 8
Neoplastic	p. 19
Multiple Sclerosis	p. 19
Case History Problem Solving Part II: Brain Stem and Cranial Nerves	p. 9
Lesion Diagrams	p. 1
Case Histories	p. 2
Diencephlaon	p. 21
Introduction	p. 1
Nuclei of the thalamus	p. 2
Functional organization of Thalamus	p. 3
White Matter of the diencephalon	p. 7
Relationship between the thalamus and the cerebral cortex	p. 8
Subthalamus	p. 9
Major Sensory Pathways of the CNS	p. 12
Major Systems
Hypothalamus, Neuroendocrine and Autonomic systems	p. 16
Introduction	p. 1
Hypothalamus	p. 2
Neuroendocrine systems	p. 5
Hormnes produced in by hypothalamus	p. 7
Hormones produced by Adenohypophysis	p. 7
Hypothalamus and the Autonomic system	p. 10
Hypothalamus and Emotions	p. 11
Autonomic Nervous system	p. 12
Cerebral cortex, Cytoarchitecture, Functional localization	p. 28
Anatomy	p. 1
Functional localization	p. 8
Subcortical white matter	p. 16
Neurophysiology and Seizure Correlations	p. 24
Motor System I: Reflex Activity and Cortical Motor Function	p. 26
Reflexes and central pattern generators	p. 1
Motor functions of cerebral cortex	p. 8
Primary Motor Cortex	p. 10
Premotor Cortex	p. 16
Pyramidal Tract	p. 17
Cortical control of eye movements	p. 19
Prefrontal cortex	p. 23
Gait disorders in the elderly	p. 25
Motor System III: Basal Ganglia and Movement Disorders	p. 24
Structure, connections, transmitters	p. 1
Parkinson's disease	p. 7
Choreiform disorders	p. 15
Other dyskinesias	p. 21
Motor System III: Cerebellum and Movement	p. 22
Anatomy	p. 1
Syndromes of the lobes	p. 6
Vascular Syndromes	p. 14
Spinocerebellar Degenerations	p. 16
Overview of Tremor	p. 21
Somatosensory Function and the Parietal Lobe	p. 10
PostCentral gyrus and Syndromes	p. 1
Parietal lobules
Dominant Hemisphere syndromes	p. 7
Non-Dominant Hemisphere Syndromes	p. 8
Limbic System	p. 27
Anatomy	p. 1
Emotions	p. 6
Hippocampus	p. 8
Temporal lobe and Seizures	p. 14
Prefrontal Cortex and Emotions	p. 20
Visual system	p. 20
The eye	p. 1
The retina	p. 3
Pathways, Lesions and Syndromes	p. 7
Occipital Cortex and Syndromes	p. 12
Speech, Language, Cerebral Dominance and the Aphasias	p. 18
Language dominance and development	p. 1
Aphasia
Nnonfluent	p. 6
Nonfluent	p. 9
Visual Agnosia	p. 15
Aparaxia	p. 17
Nondominant functions	p. 17
Case History Problem Solving III: Cortical Localization	p. 9
Case Histories	p. 1
Disease of the Cerebral Hemispheres: I: Vascular Syndromes	p. 31
Ischemic occlusive	p. 1
Embolic disease
Carotid	p. 4
Middle Cerebral Artery	p. 11
Anterior Cerebral Artery	p. 16
Posterior Cerebral Artery	p. 18
Emboism	p. 19
Intracerebral hemorrhage	p. 22
Subarachnoid hemorrhage	p. 24
Disease of the Cerebral Hemispheres: II. Non Vascular	p. 34
Trauma	p. 1
Neoplasms	p. 7
Infections	p. 18
(Non bacterial on CD ROM)
System disorders
Disorders of myelin
Case History Problem Solving IV: Cerebral Hemispheres	p. 11
Lesion diagrams
Case Histories
Complex Functions
Alterations in Consciousness: Seizures, Coma, and Sleep	p. 28
Basic definitions	p. 1
Seizures and Epilepsy	p. 3
Focal Epilepsy	p. 3
General Epilepsy	p. 6
Sleep	p. 23
Coma	p. 28
Learning, Memory, Amnesia, Dementias	p. 20
Definitions	p. 1
Stages of Human Memory	p. 2
Disorders of Recent Memory	p. 5
Wernicke's Korsakoff	p. 5
Diencephalic Mechanisms	p. 6
Hippocampal Lesion	p. 7
Progressive Dementia	p. 11
Case History Problem Solving: V: Part I General Case Histories	p. 11
Case Histories	p. 1
Case History Problem Solving V: Part II General Case Histories	p. 13
Imaging Correlations Lesion Diagrams	p. A-1
Case Histories
Table of Contents--CD
Atlas PDF Format
Brain Stem Myelin Stain Still Born Levels--medulla, pons
Gross Brain Labeled Levels
Coronal
Horizontal
MRI from similar levels
Myelin Stained & Labeled Sections
Coronal
Horizontal
Sagittal
Descriptive Atlas of Brain
Spinal Cord Levels; Cervical, Thoracic, Lumbar, Sacral
Brain Stem: Medulla Levels--Junction with spinal cord, Narrow, and Wide
Pons Levels - Facial Colliculus and Trigeminal Nerve Rootlet
Midbrain Levels - Inferior Colliculus, Superior Colliculus
Thalamus: Levels - Anterior tubercle, Mid-thalamic, Posterior thalamus
Blood Supply Overview
Localization in Cerebrum
Skull
Cases in Long Format - PDF Format
Spinal Cord PNS, Embryology	p. 35
Brain Stem	p. 36
Cerebral Hemispheres: Motor system, Cerebellum Basal Ganglia	p. 110
Cerebrum: Vision, Disease Memory	p. 157
Cranial Nerve Illustrations in PDF Format
Illustrations of all the Cranial Nerves from chapter 12 in Color
Special Senses
Vestibular & Cochlear Nerves
Visual System - Chapter 23
Pathways in the CNS PDF Format
Supplemental
Psychiatric Overview
Survey of Pathology
Table of Contents provided by Rittenhouse. All Rights Reserved.

Integrated Neuroscience

A Clinical Problem Solving Approach

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

Paperback

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