Y Chromosome And Male Germ Cell Biology In Health And Diseases, The

By: Chris Yun-fai Lau (Editor), Wai-yee Chan (Editor)

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Hardcover | 19 April 2007

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324 Pages

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22.86 x 15.88 x 1.91

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The completion of the human genome and technological advances developed by the Human Genome Project have dramatically changed our understanding of the mechanisms underlying the development and differentiation of male germ cells, and our ability to investigate such mechanisms. This book is a timely document of advances made in the field of male gonad and germ cell research in the postgenomic era.The coverage includes the role of Y chromosome genes in male reproduction, gene expression in spermatogonial stem cells and male germ cells, and the regulation of germ cell genes in reproduction and in germ cell tumors.

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Foreword	p. v
The roles of mouse Y chromosome genes in spermatogenesis	p. 1
Male meiotic sex chromosome inactivation and meiotic silencing	p. 27
Insights into SRY action from sex reversal mutations	p. 47
The TSPY gene family	p. 73
Structure and function of AZFa locus in human spermatogenesis	p. 91
RBMY and DAZ in spermatogenesis	p. 127
Neurotrophic factors in the development of the postnatal male germ line	p. 149
Dickkopf-like 1 - a protein unique to mammals that is associated both with formation of trophoblast stem cells and with spermatogenesis	p. 185
Antisense transcription in developing male germ cells	p. 201
The spermatogonial stem cell model	p. 221
Transplantation of germ cells and testis tissue	p. 235
Orthodox and unorthodox ways to initiate fertilization and development in mammals	p. 255
Pathogenesis of testicular germ cell tumors	p. 263
Origin of testicular germ cell neoplasia: the role of sex chromosomes	p. 289
Author Index	p. 309
Index	p. 311
Table of Contents provided by Ingram. All Rights Reserved.

Y Chromosome And Male Germ Cell Biology In Health And Diseases, The

At a Glance

Hardcover

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