The Laboratory Mouse

Part 1 History and Genetics *1.1 Origin and Phylogenetic Relationship of the Laboratory Mouse *1.2 Historical Foundations*1.3 Strains, Stocks and Mutant Mice *1.4 Mouse Genomics *1.5 Generation of Mouse Mutants by Genotype-driven Mutagenesis Part 2 Anatomy and Normative Biology *2.1 Early Mouse Development*2.2 Gross Anatomy*2.3 Histology *2.4 Skin and Adnexa of the Laboratory Mouse *2.5 Development and Disease of Mouse Muscular and Skeletal Systems*2.6 The Cardiovasular System *2.7 The Respiratory Tract *2.8 The Gastrointestinal System and Metabolism*2.9 Hematology *2.10 Studying Immunology in Mice*2.11Behaviour *2.12 Biological Rhythm of the Mouse Part 3 Neoplasms and Infectious Diseases *3.1 Diversity of Spontaneous Neoplasms in commonly used Inbred Strains of Laboratory Mice *3.2 Viral Infections *3.3 Bacterial Infections of the Laboratory Mouse*3.4 Parasitic Infections of the Laboratory Mouse Part 4 Husbandry and Maintenance *4.1 Housing and Maintenance *4.2 Mouse Enrichment *4.3 Nutrition of the Laboratory Mouse*4.4 Health Management and Monitoring*4.5 Genetic Monitoring*4.6 Gnotobiology and Breeding Techniques*4.7 Cryopreservation of Pre-implantation Embryos and Gametes and associated Methods Part 5 Procedures *5.1 Handling and Restraint *5.2 Routes of Administration *5.3 Collection of Body Fluids *5.4 Anaesthesia, Analgesia and Euthanasia *5.5 Imaging the Laboratory Mouse in vivo *5.6 Necropsy Methods Part 6 Legal Regulations *6.1 Laws, Guidelines and Policies governing the Use of Mice in Research