The Heparins

Basic and Clinical Aspects

By: Green

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Paperback | 13 January 2020 | Edition Number 1

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216 Pages

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22.86 x 15.24 x 1.17

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More than 30 tons of the anticoagulant, heparin, are produced annually, making it one of the most widely used drugs worldwide. It is a major pharmaceutical whose properties and clinical applications continue to be investigated and examined. The Heparins-Unfractionated, Low Molecular Weight, and Non-Anticoagulant describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of the various heparins are illustrated, and their function as anticoagulants delineated. Dr. Green is an internationally known hematologist with 45 years of clinical and research experience and an expert on bleeding and clotting disorders. This resource arms researchers and clinicians with a concise and practical source of information about the heparins, assisting biomedical research and medical practice and ultimately improving patient outcomes.

Provides a clinical perspective on the properties of the heparins, their indications and adverse effects, and the new products in development
Describes new pharmaceuticals derived from heparin that are devoid of anticoagulant activity but retain anti-inflammatory and anti-proliferative properties
Discusses development of non-anticoagulant heparins for the treatment of diseases ranging from asthma to cancer
Describes the history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders

Industry Reviews

"This is a useful addition to the library of hematologists, internists, pathologists, and other clinicians who use anticoagulant therapy. It is a helpful reference for the history of drug development and clinical trials in this area of medicine. Although many textbooks of hematology and internal medicine will contain some of this information, I am not aware of another recent book with this comprehensive focus." --Doody

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