Methods in Molecular Biology

1. The ICH S5(R2) Guideline for the Testing of Medicinal Agents L. David Wise 2. Non-Clinical Reproductive Toxicity Testing Requirements for Drugs, Pesticides, and Industrial Chemicals in India and China K.S. Rao and Jing Dong 3. The Developmental Toxicity Testing of Biologics Keith P Hazelden 4. The OECD Guidelines for the Testing of Chemicals and Pesticides Jochen Buschmann 5. Teratology Testing Under REACHSteve Barton 6. The Teratology Testing of Food Additives Paul Barrow and Francois Spezia 7. Developmental Toxicity Testing of Vaccines Paul Barrow and Linda Allais 8. The Tratology Testing of Cosmetics Francois Spezia and Paul Barrow 9. Teratology Studies in the Rat Mariline Leroy and Linda Allais 10. Teratology Studies in the Mouse Edward Marsden and Mariline Leroy 11. Combined Fertility and Embryotoxicity Study Lucie Reynaud and Edward Marsden 12.Teratology Studies in the Rabbit Linda Allais and Lucie Reynaud 13. Teratology Studies in the Minipig Peter A. McAnulty 14. Embryofetal Development Studies in Nonhuman Primates Antje Fuchs, Eberhard Buse, Gerhard F. Weinbauer 15. The Enhanced Pre- and Post-natal Development Study for Monoclonal Antibodies Gerhard F Weinbauer, Joerg Luft, and Antje Fuchs 16. Skeletal Examination by Alizarin Staining Lucie Reynaud and Audrey Jocteur-Monrozier 17. Skeletal Examination by Double Staining for Ossified Bone and Cartilaginous Tissue Steffen Schneider 18. Small Animal Imaging and Examination by Micro-CT Sergio X. Vasquez, Neha Shah, Alan M. Hoberman 19. Fetal Soft Tissue Examination by Serial Sectioning Karon Critchell Huntingdon 20. Fetal Soft Tissue Examinations by Microdissection Mariline Leroy and Audrey Jocteur Monrozier 21. Soft Tissue Examination Of The Fetal Rat And Rabbit Head By Magnetic Resonance Imaging Julian M French and Neil Woodhouse 22. Historical Control Data in Reproductive and Developmental Toxicity Studies Eve Mylchreest 23. Reporting of Teratology Studies Paul Barrow and Lucie Reynaud 24. Maternal Toxicity Bengt R Danielsson 25. Innovations in Testing Strategies in Reproductive Toxicology Aldert H. Piersma 26. Predictive Models and Computational Toxicology Thomas Knudsen, Matthew Martin, Kelly Chandler, Nicole Kleinstreuer, Richard Judson, and Nisha Sipes 27. The Embryonic Stem Cell Test Sjors H.W. Schulpen and Aldert H. Piersma 28. Zebrafish Teratogenicity Testing Kimberly C. Brannen, Jeffrey H. Charlap, and Elise M. Lewis 29. Frog Embryo Teratogenesis Assay on Xenopus (FETAX) and Predictivity Compared with In-vivo Mammalian Studies I. Leconte and I. Mouche 30. The Rat Whole Embryo Culture Assay using the Dysmorphology Score System Cindy Zhang, Julie Panzica-Kelly, Karen Augustine-Rauch 31. Toxicogenomic Approaches in Developmental Toxicology Testing Joshua F. Robinson and Aldert H. Piersma 32. Validation of Alternative Tests for Developmental and Reproductive Toxicology Testing - An ILSI Health and Environmental Sciences Institute Perspective James H. Kim 33. Regulatory Assessment of Reproductive Toxicology Data Elizabeth Davidson 34. Hazard and Risk Assessment of Teratogenic Chemicals under REACH Wiebke Prutner 35. Reproductive Toxicity Risk Assessment for Pesticides Beate Ulbrich 36. The Thalidomide Disaster, Lessons from the PastJames E Ridings Keith P Hazelden 4. The OECD Guidelines for the Testing of Chemicals and Pesticides Jochen Buschmann 5. Teratology Testing Under REACHSteve Barton 6. The Teratology Testing of Food Additives Paul Barrow and Francois Spezia 7. Developmental Toxicity Testing of Vaccines Paul Barrow and Linda Allais 8. The Tratology Testing of Cosmetics Francois Spezia and Paul Barrow 9. Teratology Studies in the Rat Mariline Leroy and Linda Allais 10. Teratology Studies in the Mouse Edward Marsden and Mariline Leroy 11. Combined Fertility and Embryotoxicity Study Lucie Reynaud and Edward Marsden 12.Teratology Studies in the Rabbit Linda Allais and Lucie Reynaud 13. Teratology Studies in the Minipig Peter A. McAnulty 14. Embryofetal Development Studies in Nonhuman Primates Antje Fuchs, Eberhard Buse, Gerhard F. Weinbauer 15. The Enhanced Pre- and Post-natal Development Study for Monoclonal Antibodies Gerhard F Weinbauer, Joerg Luft, and Antje Fuchs 16. Skeletal Examination by Alizarin Staining Lucie Reynaud and Audrey Jocteur-Monrozier 17. Skeletal Examination by Double Staining for Ossified Bone and Cartilaginous Tissue Steffen Schneider 18. Small Animal Imaging and Examination by Micro-CT Sergio X. Vasquez, Neha Shah, Alan M. Hoberman 19. Fetal Soft Tissue Examination by Serial Sectioning Karon Critchell Huntingdon 20. Fetal Soft Tissue Examinations by Microdissection Mariline Leroy and Audrey Jocteur Monrozier 21. Soft Tissue Examination Of The Fetal Rat And Rabbit Head By Magnetic Resonance Imaging Julian M French and Neil Woodhouse 22. Historical Control Data in Reproductive and Developmental Toxicity Studies Eve Mylchreest 23. Reporting of Teratology Studies Paul Barrow and Lucie Reynaud 24. Maternal Toxicity Bengt R Danielsson 25. Innovations in Testing Strategies in Reproductive Toxicology Aldert H. Piersma 26. Predictive Models and Computational Toxicology Thomas Knudsen, Matthew Martin, Kelly Chandler, Nicole Kleinstreuer, Richard Judson, and Nisha Sipes 27. The Embryonic Stem Cell Test Sjors H.W. Schulpen and Aldert H. Piersma 28. Zebrafish Teratogenicity Testing Kimberly C. Brannen, Jeffrey H. Charlap, and Elise M. Lewis 29. Frog Embryo Teratogenesis Assay on Xenopus (FETAX) and Predictivity Compared with In-vivo Mammalian Studies I. Leconte and I. Mouche 30. The Rat Whole Embryo Culture Assay using the Dysmorphology Score System Cindy Zhang, Julie Panzica-Kelly, Karen Augustine-Rauch 31. Toxicogenomic Approaches in Developmental Toxicology Testing Joshua F. Robinson and Aldert H. Piersma 32. Validation of Alternative Tests for Developmental and Reproductive Toxicology Testing - An ILSI Health and Environmental Sciences Institute Perspective James H. Kim 33. Regulatory Assessment of Reproductive Toxicology Data Elizabeth Davidson 34. Hazard and Risk Assessment of Teratogenic Chemicals under REACH Wiebke Prutner 35. Reproductive Toxicity Risk Assessment for Pesticides Beate Ulbrich 36. The Thalidomide Disaster, Lessons from the PastJames E Ridings