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T Lymphocytes : Structure, Function and Choices

By: Benvenuto Pernis (Editor), Franco Celada (Editor)

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Hardcover

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Hardcover
272 Pages

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26.0 x 17.78 x 1.6

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Elucidates the structure and function of T lymphocytes, the commanding elements of the immune system, providing a balance between the basic principles and latest experimental findings of cellular immunology; and the hypotheses, speculations, and new projections that will inform the field during the

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Nature & The Natural World Science Biology, Life Sciences Botany & Plant Sciences Zoology & Animal Sciences

T-cell antigen and MHC recognition: Molecular analysis of human [alpha/beta] TCR specific for a tetanus toxin-derived peptide	p. 1
Structure of the TCR-Ag-MHC complex	p. 17
Is recognition by the T cell receptor highly constrained or very degenerate?	p. 25
Characteristics of foreign and self peptides endogenously bound to MHC class I molecules	p. 37
Positive and negative selection of T cells	p. 45
Peripheral tolerance	p. 61
The functional relationship between preferential use of newly synthesized class II molecules and their stable association with peptides	p. 71
Epitope selection and autoimmunity	p. 75
HLA-A2 allorecognition and subtyped diversification	p. 89
On the anitigenicity of antibody idiotypes	p. 97
Idiotype interactions between T cells	p. 105
A network of self interactions	p. 111
Stimulation of lymphocytes by anti-idiotypes bearing the internal image of viral antigens	p. 121
Cloned suppressor T cells -- their identity, functions and mediators	p. 135
The autoreactive T cell receptor: Structure and biological activity	p. 145
The relationship between diabetes and lymphopenia in the BB rat	p. 153
RT6, an unusually polymorphic T cell specific membrane protein linked to type I autoimmune diabetes in rats and mice	p. 163
Alternative pathways of signal transduction after ligation of the TCR by bacterial superantigen	p. 169
Molecular analysis of the interactions between staphylococcal enterotoxin A superantigen and the human MHC class II molecules	p. 179
Immunosuppression by MHC class II blockade	p. 187
Recognition of HIV antigens by human T helper cells	p. 195
Proliferative responses to the V3 region of HIV envelope are enhanced following immunization with V3: Ty virus-like particles in mice	p. 207
Teaching immunology: a Montessori approach using a computer model of the immune system	p. 215
Modelling T cell memory in vivo and in vitro	p. 227
Oligoclonal T cells expressing the TCR V[beta]6 gene product following IL-2 culture of ovarian carcinoma-derived lymphocytes	p. 235
Comparisons of the V-delta-1 expressing T cells in synovial fluid and peripheral blood of patients with chronic arthritis	p. 241
Bispecific monoclonal antibody-targeted cytotoxic T lymphocytes can recycle	p. 247
Index	p. 251
Table of Contents provided by Blackwell. All Rights Reserved.

T Lymphocytes : Structure, Function and Choices

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Hardcover

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