Stem Cell Aging

Mechanisms, Consequences, Rejuvenation

By: Hartmut Geiger (Editor), Maria Carolina Florian (Editor), Heinrich Jasper (Editor)

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Hardcover | 31 July 2015

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Hardcover
368 Pages

Dimensions(cm)
16.6 x 24.3 x 2.0

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$169.00

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Aging of somatic stem cells reduces stem cell function and results in dysfunctional organs and tissues. Aging of stem cells is thus an underlying cause for aging associated diseases. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis like skin, blood, intestine. Understanding molecular and cellular mechanisms of aging of stem cells is critical for developing approaches to attenuate stem cell aging and it might pave avenues for a healthier life in the elderly. This book presents our current knowledge on mechanisms of aging of stem cells, written by highly prominent experts in the field. It gives insight into stem cell function, comprehensively explains the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches on how to attenuate stem cell aging or attain rejuvenation. The book is written for scientists and clinicians working with stem cells, aging mechanism and age related diseases.

Industry Reviews

"This book discusses the impact of aging on the many stem cell populations, the pathologies associated with the decline of stem cell functions, and the use of stem cells to attenuate stem cell aging. ... The purpose is to provide a reference for researchers working in the field of healthy aging. The audience is clinicians and all scientists working in the field of aging, stem cells, and regenerative medicine." (Michele Fornaro, Doody's Book Reviews, October, 2015)

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