Restriction Endonucleases

By: A. Pingoud, Alfred M. Pingoud

Write A Review

Hardcover | 19 February 2004

At a Glance

Hardcover
472 Pages

Dimensions(cm)
23.5 x 15.88 x 3.18

Hardcover

$329.00

or 4 interest-free payments of $82.25 with

or

Ships in 7 to 10 business days

Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.

Shipping

	Standard Shipping	Express Shipping
Metro postcodes:	$9.99	$14.95
Regional postcodes:	$9.99	$14.95
Rural postcodes:	$9.99	$14.95

Orders over $79.00 qualify for free shipping.

How to return your order

At Booktopia, we offer hassle-free returns in accordance with our returns policy. If you wish to return an item, please get in touch with Booktopia Customer Care.

Additional postage charges may be applicable.

Defective items

If there is a problem with any of the items received for your order then the Booktopia Customer Care team is ready to assist you.

For more info please visit our Help Centre.

More in Biology, Life Sciences

Liars, cheats and copycats

Trickery and deception in nature

Paperback

RRP $34.99

$29.99

14%
OFF

Grant's Atlas of Anatomy

16th Edition

Paperback

RRP $187.99

$159.79

15%
OFF

Children Of Dune

The inspiration for the blockbuster film

Hardcover

RRP $55.00

$42.75

22%
OFF

Is a River Alive?

Paperback

RRP $26.99

$22.99

15%
OFF

Netter Atlas of Human Anatomy

8th Edition - Classic Regional Approach

Paperback

RRP $151.95

$116.75

23%
OFF

Protein in 15

Easy, tasty, unprocessed meals for everyone by The Body Coach

Hardcover

RRP $45.00

$29.99

33%
OFF

Principles of Anatomy and Physiology

3rd Asia Pacific Edition

Paperback

RRP $180.95

$153.75

15%
OFF

Death by Comfort

How modern life is killing us and what we can do about it

Paperback

RRP $32.99

$26.99

18%
OFF

A Guide to Native Bees of Australia

Paperback

RRP $49.99

$40.75

18%
OFF

Gray's Anatomy for Students

5th Edition

Paperback

RRP $159.95

$121.75

24%
OFF

Seeley's Anatomy & Physiology ISE

13th Edition

Paperback

RRP $169.95

$130.75

23%
OFF

Netter's Anatomy Coloring Book

3rd edition

Paperback

RRP $39.95

$33.75

16%
OFF

Compact Field Guide to Australian Birds

The complete pocket-sized reference

Paperback

RRP $34.99

$29.99

14%
OFF

The Anatomy Coloring Book

Paperback

RRP $33.55

$30.75

Birds of Western Australia

2nd Edition - The Field Guide

Paperback

RRP $39.99

$33.75

16%
OFF

Chemistry for the Biosciences

4th Edition - The Essential Concepts

Paperback

RRP $97.95

$82.75

16%
OFF

AFN Australian Fish Guide

AFN Fish ID

Flexi Bound Book

RRP $29.99

$24.99

17%
OFF

The Key Muscles of Yoga : Your Guide to Functional Anatomy in Yoga

Scientific Keys | Volume 1

Paperback

RRP $74.95

$51.75

31%
OFF

Australian Medicinal Plants

A Complete Guide to Identification and Usage

Paperback

RRP $49.99

$38.75

22%
OFF

Bird Bingo

Magma for Laurence King

Game

RRP $49.99

$38.75

22%
OFF

A Field Guide to Spiders of Australia

Paperback

RRP $49.95

$40.75

18%
OFF

How To Change Your Mind

New Science of Psychedelics

Paperback

RRP $26.99

$22.99

15%
OFF

The Master and His Emissary

The Divided Brain and the Making of the Western World

Paperback

RRP $36.95

$29.75

19%
OFF

Swainston's Fishes of Australia

The complete illustrated guide

Paperback

RRP $80.00

$58.99

26%
OFF

Survey and summary : a nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes	p. 1
Restriction-modification systems as minimal forms of life	p. 19
Molecular phylogenetics of restriction endonucleases	p. 63
Sliding or hopping? : how restriction enzymes find their way on DNA	p. 95
The type I and III restriction endonucleases : structural elements in molecular motors that process DNA	p. 111
The integration of recognition and cleavage : X-ray structures of pre-transition state complex, post-reactive complex and the DNA-free endonuclease	p. 137
Structure and function of EcoRV endonuclease	p. 179
Two of a kind : BamHI and BglII	p. 215
Structure and function of the tetrameric restriction enzymes	p. 237
Structure and function of type IIE restriction endonucleases - or : from a plasmid that restricts phage replication to a new molecular DNA recognition mechanism	p. 261
Analysis of type II restriction endonucleases that interact with two recognition sites	p. 297
The role of water in the EcoRI-DNA binding	p. 319
Role of metal ions in promoting DNA binding and cleavage by restriction endonucleases	p. 339
Restriction endonucleases : structure of the conserved catalytic core and the role of metal ions in DNA cleavage	p. 361
Protein engineering of restriction enzymes	p. 393
Engineering and applications of chimeric nucleases	p. 413
Table of Contents provided by Blackwell. All Rights Reserved.

Restriction Endonucleases

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

Paperback

More in Biology, Life Sciences

Liars, cheats and copycats

Trickery and deception in nature

Grant's Atlas of Anatomy

16th Edition

Children Of Dune

The inspiration for the blockbuster film

Is a River Alive?

Netter Atlas of Human Anatomy

8th Edition - Classic Regional Approach

Protein in 15

Easy, tasty, unprocessed meals for everyone by The Body Coach

Principles of Anatomy and Physiology

3rd Asia Pacific Edition

Death by Comfort

How modern life is killing us and what we can do about it

A Guide to Native Bees of Australia

Gray's Anatomy for Students

5th Edition

Seeley's Anatomy & Physiology ISE

13th Edition

Netter's Anatomy Coloring Book

3rd edition

Compact Field Guide to Australian Birds

The complete pocket-sized reference

The Anatomy Coloring Book

Birds of Western Australia

2nd Edition - The Field Guide

Chemistry for the Biosciences

4th Edition - The Essential Concepts

AFN Australian Fish Guide

AFN Fish ID

The Key Muscles of Yoga : Your Guide to Functional Anatomy in Yoga

Scientific Keys | Volume 1

Australian Medicinal Plants

A Complete Guide to Identification and Usage

Bird Bingo

Magma for Laurence King

A Field Guide to Spiders of Australia

How To Change Your Mind

New Science of Psychedelics

The Master and His Emissary

The Divided Brain and the Making of the Western World

Swainston's Fishes of Australia

The complete illustrated guide

This product is categorised by