Proteinâ"Protein Interaction Regulators

By: Haian Fu (Editor), Siddhartha Roy (Editor)

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Hardcover | 15 January 2020

At a Glance

Hardcover
398 Pages

Dimensions(cm)
16.2 x 24.1 x 2.8

Hardcover

$549.99

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New genomic information has revealed the crucial role that protein-protein interactions (PPIs) play in regulating numerous cellular functions. Aberrant forms of these interactions are common in numerous diseases and thus PPIs have emerged as a vast class of critical drug targets. Despite the importance of PPIs in biology, it has been extremely challenging to convert targets into therapeutics and targeting PPIs had long been considered a very difficult task. However, over the past decade the field has advanced with increasing growth in the number of successful PPI regulators. Protein-Protein Interaction Regulators surveys the latest advances in the structural understanding of PPIs as well as recent developments in modulator discovery.

Molecular interations, protein-protein interactions play a crucial role in regulating many cellular functions. In many diseases, abberant forms of these interactions play central roles. Thus, they have emerged as critical drug targets. This book includes a survey of recent advances in the structural understanding of protein-protein interactions, as well as recent developments in modulator discovery.

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