| Pathology of variant Creutzfeldt-Jakob disease | p. 1 |
| Clinical aspects of variant CJD | p. 15 |
| Dura mater related Creutzfeldt-Jakob disease in Japan : relationship between sites of grafts and clinical features | p. 31 |
| Treatment options in patients with prion disease - the role of long term cerebroventricular infusion of pentosan polysulphate | p. 41 |
| Human prion diseases : novel diagnostic principles | p. 67 |
| History and state of the art of PrP-res "typing" in Creutzfeldt-Jakob disease | p. 77 |
| Chronic wasting disease in cervids in North America | p. 97 |
| Bovine spongiform encephalopathy (BSE) in Japan | p. 99 |
| The role of host PrP in control of incubation time | p. 109 |
| The role of the immune system in TSE agent neuroinvasion | p. 119 |
| Prion protein interactions and TSE infections in cell culture models | p. 141 |
| Semi-classical quantization of protein dynamics : novel NMR relaxation formalism and its application to prion | p. 155 |
| Surveillance of chronic wasting disease (CWD) in Japan | p. 171 |
| Unexpected high incidence of visceral AA-amyloidosis in slaughtered cattle in Japan | p. 173 |
| A Novel BSE screening kit with simplified preparation method for EIA | p. 175 |
| Detection of recombinant bovine prion protein by fluorescence correlation spectroscopy | p. 177 |
| PrPSc distribution of a natural case of bovine spongiform encephalopathy | p. 179 |
| Report of the first oral inoculation of BSE prion into cattle in Japan | p. 181 |
| The development of the intracerebral inoculation method and BSE experimental transmissions to calves | p. 183 |
| Comparative analyses of three mouse-adapted scrapie strains G1, Obihiro, and I3/I5 and pathogenesis of G1 strain-induced polyuria in ICR mice | p. 185 |
| Dose effect on detection of PrP[superscript Sc] in follicular dendritic cells of knock-in mice for rapid bioassay | p. 187 |
| Cell surface retention of PrP[superscript C] by anti-PrP antibody prevents protease-resistant PrP formation | p. 189 |
| Prion-conformation-specific human antibodies established from phage display library | p. 191 |
| Partial characterization of monoclonal antibodies which bind to disease-associated prion protein in immunoprecipitaion assay | p. 193 |
| Production and characterization of monoclonal antibodies specific for prion protein | p. 195 |
| In vitro selection of anti-mouse priori protein RNA aptamers | p. 197 |
| Detection of the prion protein in a liquid phase capture assay using magnetic beads coupled to protein A | p. 199 |
| New pretreatment method for immunohistochemistry for abnormal prion protein | p. 201 |
| Cellular prion protein suppresses the apoptosis in a neuronal cell line established from type-1 prion protein gene-deficient mice | p. 203 |
| Cellular prion protein suppressess the apoptotic cell death by mediating the intracellular H[subscript 2]O[subscript 2] in primary culture and immortalized neuronal cells | p. 205 |
| Targeting of cytosolic PrP[superscript C] via a novel 14-3-3-Tom 70-mitochondrial BCL-2 pathway induces mitochondrial apoptosis | p. 207 |
| Microtubule-dependent intracellular trafficking of cellular prion protein | p. 209 |
| Hsp90 modifies the conformation of recombinant mouse prion protein in vitro | p. 211 |
| Purification and characterization of a novel ATP-dependent robust protein-unfoldase, unfoldin | p. 213 |
| Nucleic acid and prion protein interaction produces spherical amyloids which in vivo can function as coats of spongiform encephalopathy agent | p. 215 |
| Species barrier in yeast [PSI[superscript +]] prion transmission | p. 217 |
| Molecular memory of [PSI[superscript +]] prion strains in S. cerevisiae is dependent on the primary structure of the Sup35 prion domain | p. 219 |
| Expression of a splice variant of prion protein during hypoxia in human glioblastoma cell line T98G | p. 221 |
| PRNP promoter region polymorphism in Creutzfeldt-Jakob disease | p. 223 |
| Tubulovesicular structures are consistently found in prion diseases including vCJD and FFI | p. 225 |
| Autophagy is a common ultrastructural feature of neuropathology of prion diseases | p. 227 |
| Type 1 and type 2 human PrP[superscript Sc] have different aggregation sizes in methionine homozygotes with sporadic, iatrogenic and variant Creutzfeldt-Jakob disease | p. 229 |
| A pitfall in diagnosis of human prion diseases using detection of protease-resistant prion protein in urine : contamination with bacterial outer membrane proteins | p. 231 |
| Comparative analysis of chronological data of total tau protein in CSF, serial studies of MRI (DWI, and FLAIR) and staging of clinical features in patients with sporadic CJD | p. 233 |
| Duration between initial manifestation of CJD and detection of PSD, specific findings on MRI, CSF 14-3-3 protein, or CSF high NSE | p. 235 |
| Biochemical analysis of peripheral tissue involvement in transmissible spongiform encephalopathies | p. 237 |
| Involvement of the peripheral nervous system in human prion diseases including dural graft-associated Creutzfeldt-Jakob disease | p. 239 |
| MM2 type sporadic Creutzfeldt-Jakob disease : clinicoradiologic features and clinical diagnosis | p. 241 |
| Early clinical and radiological diagnosis of sporadic Creuzfeldt-Jakob's disease (sCJD) - a case study of pathologically-proved sCJD MV2 | p. 245 |
| Familial Creutzfeldt-Jakob disease with a point mutation (Met to Arg) at codon 232 : two different phenotypes | p. 247 |
| Familial Creutzfeldt-Jakob disease with five octapeptide repeat insert | p. 249 |
| A case of Creutzfeldt-Jakob disease with a novel insertion mutation and codon 219 lysine/lysine polymorphism in the prion protein gene | p. 251 |
| Inhibition of prion propagation in scrapie-infected cell lines using mouse monoclonal antibodies against prion protein | p. 253 |
| The inhibitory effect of the ScFv of an anti-prion protein antibody secreted from N2a58 cells on abnormal prion protein accumulation in scrapie-infected cells, ScN2a | p. 255 |
| Mucosal immunogenicity of prion protein fused with heat-labile enterotoxin B subunit | p. 257 |
| Identification of drugs that enhance the stimulatory effect of PrP on the fibrinolytic system | p. 259 |
| Screening study of prion binding agents and their inhibitory effect on the conversion of prion protein | p. 261 |
| Can forage grasses inhibit prion replication? | p. 263 |
| Inhibition of abnormal PrP formation by amyloid-imaging probes in vitro | p. 265 |
| Treatment with anti-malaria agents, quinacrine and quinine, for Creutzfeldt-Jakob disease patients | p. 267 |
| Effect of oral administration of pentosan polysulfate for patients with Creutzfeldt-Jakob disease (CJD) and new design for low molecular-weight of pentosan polysulfate | p. 269 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
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