Population Genetics

A Concise Guide

By: John H. Gillespie

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Hardcover | 14 October 2004 | Edition Number 2

At a Glance

Hardcover
232 Pages

Edition Type
Revised

Age
22+

Dimensions(cm)
22.86 x 15.24 x 1.91

Hardcover

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This concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Industry Reviews

"John Gillespie has done the near-impossible, condensing the essence of population genetics into a very short book. The result is a little gem. The derivations are simple and clear, and often strikingly original. The minor gaps in the first edition are filled by this equally concise second edition. Population genetics is a complicated subject; only a person of Gillespie's depth of knowledge and insight could simplify without distorting." - James F. Crow, author of Genetics Notes "The book is coherently and logically structured and covers all the most important and incontrovertible aspects of population genetics... I recommend this as a good introductory book that can be used in both undergraduate and graduate courses." - Heredity "A well-developed, thoughtful, and classic book that has been tested and improved through many years in the classroom... A 'must' for anyone interested in plant or animal genetics." - Choice"

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Life Sciences in General Genetics excluding Medical Science in General Evolution Medicine Pre-Clinical Medicine & Basic Sciences Medical Genetics Ecological Science

List of Figures	p. ix
Preface	p. xi
Genetic Variation	p. 1
DNA variation in Drosophila	p. 2
Loci and alleles	p. 6
Genotype and allele frequencies	p. 10
The Hardy-Weinberg law	p. 12
Answers to problems	p. 18
Genetic Drift	p. 21
A first look at genetic drift	p. 22
The decay of heterozygosity	p. 25
Mutation and drift	p. 29
Molecular evolution	p. 32
The neutral theory	p. 36
The coalescent	p. 40
The effective size of a population	p. 47
Another model of genetic drift	p. 49
The stationary distribution	p. 53
Is genetic drift important in evolution?	p. 55
Answers to problems	p. 56
Natural Selection	p. 59
The fundamental model	p. 61
Relative fitness	p. 62
Three kinds of selection	p. 64
Mutation-selection balance	p. 70
Genetic load	p. 71
The heterozygous effects of alleles	p. 76
Changing environments	p. 85
The stationary distribution	p. 90
Selection and drift	p. 91
Molecular evolution	p. 95
Answers to problems	p. 98
Two-Locus Dynamics	p. 101
Linkage disequilibrium	p. 101
Two-locus selection	p. 105
Genetic draft	p. 111
Answers to problems	p. 116
Nonrandom Mating	p. 119
Generalized Hardy-Weinberg	p. 120
Identity by descent	p. 121
Inbreeding	p. 123
The evolution of selfing	p. 127
Subdivision	p. 131
Answers to problems	p. 136
Quantitative Genetics	p. 139
Correlation between relatives	p. 139
Response to selection	p. 150
Evolutionary quantitative genetics	p. 154
Dominance	p. 160
The intensity of selection	p. 166
Answers to problems	p. 168
The Evolutionary Advantage of Sex	p. 169
Genetic segregation	p. 170
Crossing-over	p. 173
Muller's ratchet	p. 174
Kondrashov's hatchet	p. 179
Answers to problems	p. 183
Mathematical Necessities	p. 185
Probability	p. 189
Bibliography	p. 207
Index	p. 211
Table of Contents provided by Ingram. All Rights Reserved.

Population Genetics

A Concise Guide

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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