Polymer and Cell Dynamics

Multiscale Modelling and Numerical Simulations

By: W. Alt, Wolfgang Alt (Editor), Mark Chaplain (Editor)

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Hardcover | 25 August 2003

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324 Pages

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24.13 x 17.78 x 2.54

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Polymer and cell dynamics play an important role in processes like tumor growth, metastasis, embryogenesis, immune reactions and regeneration. This volume - based on an international workshop on numerical simulations of polymer and cell dynamics in Bad Honnef (Germany) in 2000 - provides an overview of the relevant mathematical and numerical methods, their applications and limits. The contributions are from the fields of applied and numerical mathematics, scientific computing, theoretical physics, molecular biophysics, cell and molecular biology as well as chemical and biomedical engineering. The volume will be of interest to scientists and advanced undergraduates in the fields of biotechnology, biomedicine, applied mathematics, biomathematics, biophysics and bioinformatics.

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Published: 12th November 2012

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Preface
Introduction
Molecular Dynamics Studies of Micelle and Capsid Self-assembly	p. 7
A Functional Study on Saposin B and C Using Experimentally Validated Models	p. 19
A Review of the Morph Server and the Macromolecular Motions Database: A Standardized System for Analyzing and Visualizing Macromolecular Motions in a Database Framework	p. 29
Brownian Dynamics of Flexible Polymers in Flow	p. 49
A Microscopic Model for the Dynamics of Actin Filaments in Motility Assays and Its Numerical Simulation	p. 69
Multiparticle Modeling of Actin-Myosin Networks: From Molecular Interactions to Cell Motility	p. 75
Analysis of Cell Motility Combining Cytomechanical Model Simulations and an Optical Flow Method	p. 91
Micropipet Aspiration of the Human Neutrophil	p. 113
Physical-object-oriented 3D Simulations of Cell Deformations and Migration	p. 125
Computational Modeling of Blood Clotting: Coagulation and Three-dimensional Platelet Aggregation	p. 145
Space- and Time-resolved Simulations of Processes in Biofilm Systems on a Microscale	p. 155
On Selected Individual-based Approaches to the Dynamics in Multicellular Systems	p. 169
Individual-based Models of Cohort Migration in Cell Cultures	p. 205
Interactive Movement, Aggregation, and Swarm Dynamics	p. 221
A Discrete-cell Model of Tissue-equivalent Compaction	p. 243
A Hybrid Discrete-continuum Technique for Individual-based Migration Models	p. 251
Application of the Hybrid Discrete-continuum Technique	p. 261
List of contributors and workshop participants	p. 281
Index	p. 285
Table of Contents provided by Blackwell. All Rights Reserved.

Polymer and Cell Dynamics

Multiscale Modelling and Numerical Simulations

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Hardcover

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