Pas Proteins

Regulators and Sensors of Development and Physiology

By: Stephen T. Crews (Editor)

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Hardcover | 30 September 2003

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Hardcover
280 Pages

Dimensions(cm)
23.5 x 15.88 x 1.91

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PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.

Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.

PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Biochemistry Proteins Medicine Pre-Clinical Medicine & Basic Sciences Medical Genetics Other Branches of Medicine Pathology Medical Microbiology & Virology Clinical & Internal Medicine

Diseases & Disorders Oncology Neurology & Clinical Neurophysiology Molecular Biology Life Sciences in General Neurosciences

Contributing Authors	p. vii
Preface	p. xi
Structure of the PAS Fold and Signal Transduction Mechanisms	p. 1
Signal Transduction in Prokaryotic PAS Domains	p. 17
bHLH-PAS Proteins in C. elegans	p. 51
Drosophila bHLH-PAS Developmental Regulatory Proteins	p. 69
Methoprene-Tolerant, a PAS Gene Critical for Juvenile Hormone Signaling in Drosophila Melanogaster	p. 109
The P160 Family of Steroid Hormone Receptor Coactivators	p. 133
The Ah Receptor	p. 149
The HIF-1 Family of bHLH-PAS Proteins: Master Regulators of Oxygen Homeostasis	p. 183
Hormones, Obesity, Learning, and Breathing - The Many Functions of Mammalian Single-Minded Genes	p. 205
PAS Proteins in the Mammalian Circadian Clock	p. 231
Index	p. 253
Table of Contents provided by Ingram. All Rights Reserved.

Pas Proteins

Regulators and Sensors of Development and Physiology

At a Glance

Hardcover

Shipping

How to return your order

Defective items

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