Science Masters

How Cancer Begins

By: Robert Weinberg

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Paperback | 8 October 1999 | Edition Number 1

At a Glance

Paperback
176 Pages

Edition Type
New edition

Age
18+

Dimensions(cm)
20.96 x 13.97 x 1.27

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Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell, Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

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You Can Find This Book In

Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Oncology Science Biology, Life Sciences Microbiology excluding Medical Science in General History of Science Miscellaneous Items Infectious & Contagious Diseases

Molecular Biology Nursing & Ancillary Services Nursing Engineering & Technology Biochemical Engineering Biotechnology

Acknowledgments	p. v
The Enemy Within: Genes, Cells, and the Nature of Cancer	p. 1
Clues to Cancer's Origins: How the Outside World Affects the Insides of Our Cells	p. 13
The Elusive Quarry: Hunting the Proto-Oncogene	p. 25
Fatal Flaws: Finding Oncogenes in Human Tumors	p. 37
A Book of Many Chapters: Multistep Tumor Development	p. 45
Fueling the Fire: Carcinogens That Aren't Mutagens	p. 55
Brake Linings: the Discovery of Tumor Suppressor Genes	p. 63
Guts: a Case Study in Cancer Development	p. 79
Defenders of the Text: Dna Repair and Its Breakdown	p. 87
Guide Proteins of the Cell: the Machinery That Controls Growth	p. 95
A Breakdown of Order: Subverting Normal Growth Control	p. 105
Immortality: Avoidance of Almost Certain Death	p. 113
Assisted Suicide: Apoptosis and the Death Program	p. 121
A Clock Without Hands: the Cell Cycle Clock Apparatus	p. 131
Many Obstacles in the Road: the Evolution of a Tumor	p. 141
An End to the Scourge: Using the Knowledge of Cancer's Causes to Develop New Cures	p. 151
Index	p. 165
Table of Contents provided by Publisher. All Rights Reserved.

Science Masters

How Cancer Begins

At a Glance

Paperback

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How to return your order

Defective items

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