Hypoxia

From Genes to the Bedside

By: Robert C. Roach (Editor), Peter D. Wagner (Editor), Peter H. Hackett (Editor)

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Hardcover | 31 January 2002

At a Glance

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464 Pages

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25.4 x 17.78 x 2.54

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Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia.

Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

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Non-Fiction Medicine Pre-Clinical Medicine & Basic Sciences Physiology Other Branches of Medicine Pathology Anatomy Clinical & Internal Medicine Cardiovascular Medicine Science Biology, Life Sciences Biochemistry

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Published: 3rd December 2010

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Published: 16th December 2012

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Tribute to John T. Reeves
John T. Reeves, MD	p. 1
From Genes to the Bedside
Genetic lessons from high altitude	p. 7
Genes, environment, and exercise	p. 13
Skeletal muscle angiogenesis	p. 21
Leukocyte-endothelial interactions in environmental hypoxia	p. 39
Training at Altitude for Sea Level Performance
Hypoxia training for sea-level performance	p. 61
The effects of altitude training are mediated primarily by acclimatization, rather than by hypoxic exercise	p. 75
High Altitude Pulmonary Edema
Update: High altitude pulmonary edema	p. 89
Comparative Biology
Phylogenetic comparison and artificial selection	p. 107
Genetic and environmental adaptation in high altitude natives	p. 133
Common themes of adaptation to hypoxia	p. 153
Erythropoietin
Biology of erythropoietin	p. 169
Lessons to better understanding of hypoxia sensing	p. 189
Erythropoietin use and abuse	p. 207
Mountain Medicine
Mountaineering in thin air	p. 225
Weight loss at high altitude	p. 237
Stress Proteins and hypoxia
The heme oxygenase system and cellular defense mechanisms	p. 249
Hypoxia-inducible factor in brain	p. 273
Transepithelial Sodium Transport
Proton-gated cation channels - neuronal acid sensors in the central and peripheral nervous system	p. 293
Structure function relationships of ENaC and its role in sodium handling	p. 305
Transepithelial sodium and water transport in the lung	p. 315
Advances in Cardiorespiratory Control in Hypoxia
Is ventilatory acclimatization to hypoxia a phenomenon that arises through mechanisms that have an intrinsic role in the regulation of ventilation at sea level?	p. 339
Roles of adenosine and nitric oxide in skeletal muscle in acute and chronic hypoxia	p. 349
The pVHL-HIF-1 system	p. 365
Frontiers in Hypoxia Research
Interval hypoxic training	p. 377
Gene transfer and metabolic modulators as new therapies for pulmonary hypertension	p. 401
Chronic mountain sickness	p. 419
Appendix
International Working Group for Chronic Mountain Sickness	p. 439
Late and Amended Abstracts	p. 441
Index	p. 443
Table of Contents provided by Blackwell. All Rights Reserved.

Hypoxia

From Genes to the Bedside

At a Glance

Hardcover

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How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

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