| List of contributors | p. vii |
| Preface | p. xi |
| Estrogens and cognition: perspectives and opportunities in the wake of the Women's Health Initiative Memory Study | |
| Women's Health Initiative Memory Study (WHIMS) program: emerging findings | p. 1 |
| Identifying risk factors for cognitive change in the Women's Health Initiative: a neural networks approach | p. 11 |
| Estrogen therapy - relationship to longevity and prevalent dementia in the oldest-old: the Leisure World Cohort Study and the 90+ Study | p. 25 |
| The critical window hypothesis: hormone exposures and cognitive outcomes after menopause | p. 32 |
| Animal studies that support estrogen effects on cognitive performance and the cholinergic basis of the critical period hypothesis | p. 45 |
| The healthy cell bias of estrogen action through regulating glucose metabolism and mitochondrial function: implications for prevention of Alzheimer's disease | p. 55 |
| Varieties of estrogenic therapy | |
| Alternative estrogenic treatment regimens and the Kronos Early Estrogen Prevention Study - Cognitive and Affective substudy (KEEPS-CA) | p. 65 |
| The use of transdermal 17ß-estradiol in the treatment of Alzheimer's disease | p. 80 |
| Alternative modes of treatment: pulsatile estradiol treatment | p. 87 |
| In search of estrogen alternatives for the brain | p. 93 |
| Potential modulators and modifiers of estrogenic effects | |
| Progesterone regulation of neuroprotective estrogen actions | p. 101 |
| Clinical data of estrogen's effects in the central nervous system: estrogen and mood | p. 110 |
| Different forms of soy processing may determine the positive or negative impact on cognitive function of Indonesian elderly | p. 121 |
| Hypothalamus-pituitary-adrenal axis activity in aging women: its impact on the brain and the potential influence of estradiol | p. 133 |
| Possible genetic factors related to hormone treatment effects | |
| Possible genetic polymorphisms related to sex steroid metabolism and dementia in women | p. 143 |
| Genetics related to sex steroids: implications for Alzheimer's disease | p. 153 |
| Apolipoprotein E, hormone therapy, and neuroprotection | p. 162 |
| Testosterone, gonadotropins, and genetic polymorphisms in men with Alzheimer's disease | p. 171 |
| Testosterone, estradiol and men, and sex hormone binding globulin | |
| Androgens and cognitive functioning in women | p. 179 |
| The role of estradiol in testosterone treatment | p. 187 |
| Endogenous testosterone levels and cognitive aging in men | p. 197 |
| Clinical trials and neuroimaging studies of testosterone in men: insights into effects on verbal memory | p. 208 |
| Testosterone therapy and Alzheimer's disease: potential for treatment and prevention in women | p. 220 |
| Endogenous estradiol and dementia in elderly men: the roles of vascular risk, sex hormone binding globulin, and aromatase activity | p. 228 |
| Testosterone regulates Alzheimer's disease pathogenesis | p. 242 |
| Gonadotropin effects | |
| Involvement of gonadotropins in cognitive function: implications for Alzheimer's disease | p. 251 |
| The role of gonadotropins and testosterone in the regulation of beta-amyloid metabolism | p. 259 |
| Epilogue | p. 269 |
| Concluding remarks | p. 271 |
| Index | p. 275 |
| Table of Contents provided by Ingram. All Rights Reserved. |
