Haemostasis

Part I. The Haemostatic System 1. The Coagulation System in Humans Anthony K. C. Chan and Nethnapha Paredes 2. Platelet Physiology Matthew D. Linden 3. The Role of the Blood Vessel Wall Nethnapha Paredes and Anthony K. C. Chan Part II. General Principles of Haemostatic Testing 4. Specimen Requirements for the Haemostasis Laboratory Linda Stang and Lesley G. Mitchell 5. Principles of Haemostasis Tests Gemma Crighton 6. Reference Ranges of Coagulation Tests Oliver Speer, Markus Schmugge, Claudia Metzger, and Manuela Albisetti 7. Lupus Anticoagulant Testing Karen Moffat, Anne Raby, and Mark Crowther Part III. Examples of Global Tests of Haemostasis 8. Activated Partial Thromboplastin Time (APTT) Vera Ignjatovic 9. Prothrombin Time (PT) and International Normalised Ratio (INR) Vera Ignjatovic 10. Thrombin Clotting Time (TCT) Vera Ignjatovic 11. Thrombin Generation Leslie R. Berry and Anthony K. C. Chan 12. Activated Clotting Time (ACT) Stephen Horton and Simon Augustin Part IV. Examples of Tests for Bleeding Disorders 13. Factor XII Assays Stephen Opat, Jenny Butler, Erica Malan, Elizabeth Duncan, and Huyen A.M. Tran 14. Fibrinogen Linda Stang and Lesley G. Mitchell 15. Platelet Counting Sylvain Salignac, Veronique Latger-Cannard, Nicole Schlegel, and Thomas Lecompte 16. Platelet Morphology Analysis Veronique Latger-Cannard, Odile Fenneteau, Sylvain Salignac, Thomas Lecompte, and Nicole Schlegel 17. Light Transmission Aggregometry Juan Pablo Frontroth 18. Platelet Flow Cytometry Matthew D. Linden Part V. Examples of Specific Assays Related to Anticoagulant Activity 19. Anti-factor Xa assay (anti-Xa) Fiona Newall 20. Reptilase Time (RT) Hratsch Karapetian 21. Protamine Titration Fiona Newall 22. Laboratory Methods for the Assay if Tissue Factor Pathway Inhibitor (TFPI) in Human Plasma Robyn Summerhayes 23. Heparin Induced Thrombocytopenia (HIT) Andreas Greinacher, Birgitt Furll, and Sixten Selleng Part VI. Examples of Tests for Inhibitors of Coagulation 24. Nijmegen-Bethesda Assay to Measure Factor VIII Inhibitors Elizabeth Duncan, Margaret Collecutt, and Alison Street 25. Kaolin Clotting Time Kottayam Radhakrishnan 26. The Dilute Russell Viper Venom Time (DRVVT) Kottayam Radhakrishnan 27. Platelet Neutralisation Test Kottayam Radhakrishnan Part VII. Examples of Tests for Increased Risk of Thrombosis 28. Antithrombin Mirta Hepner and Vasiliko Karlaftis 29. Protein C Mirta Hepner and Vasiliki Karlaftis 30. Protein S Mirta Hepner and Vasiliki Karlaftis 31. Testing for Hyperhomocysteinemia in Subjects with a History of Thromboembolic Events Using HPLC Technique Jonas Denecke 32. Anticardiolipin Antibody and Anti-Beta 2 Glycoprotetin I Assays Anne Raby, Karen Moffat, and Mark Crowther 33. Testing for Apolipoprotein (a) Phenotype Using Isoelectric Focusing and Immunoblotting Technique Claus Langer, Bertram Tambyrayah, and Ulrike Nowak-Gottl Part VIII. Examples of Measures of Fibrinolysis 34. D-Dimer and Fibrinogen/Fibrin Degradation Products Linda Stang