Gene Therapy

Scope and limitations of gene therapy, K. Sikora. Tissue-directed gene delivery systems, C.R. Middaugh et al. Retroviral vectors, W.H. Gunzburg and B. Salmons. Adenovirus vectors, C.J.A. Ring. Adeno-associated virus vectors for human gene therapy, J.S. Bartlett and R.J. Samulski. Liposome delivery systems, R.K. Scheule and S.H. Cheng. Development of mammalian artificial chromosome vectors: prospects for somatic gene transfer, Z. Larin. Infectious herpes vectors for gene therapy, J.-M.H. Vos et al. Role of animal models in gene therapy, J.R. Dorin and D.J. Porteous. Gene targeting as an approach to gene therapy, A. Porter. Cystic fibrosis, N.J. Caplen and E.W.F.W. Alton. Gene therapy for haemophilia B, K. Kurachi and J.-M. Wang. Gene therapy for adenosine deaminase deficiency, H.B. Gaspar and C. Kinnon. Cardiovascular disease, B.A. French. Cancer gene therapy I: genetic intervention strategies, L.-A. Martin and N.R. Lemoine. Cancer gene therapy II: immunomodulation strategies, J. Galea-Lauri and J. Gaken. The muscular dystrophies, C.A. Sewry and T.A. Partridge. Recent developments in gene therapy for neurological disorders, P.R. Lowenstein.