
Forecasting Product Liability Claims
Epidemiology and Modeling in the Manville Asbestos Case
By: J.B. Weinstein (Foreword by), Eric Stallard, Kenneth G. Manton
Hardcover | 25 October 2004
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428 Pages
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Industry Reviews
From the reviews:
"This monograph shows then epidemiological prediction in action and is more eloquent than most textbooks as regards to methodology and difficulties encountered with field data. It should interest far outside the circle of asbestos-related epidemiology because of its rigorous exposition, the relevance of its questions, the adequacy of the solutions offered, the discussion of its results, and its legal, financial, and human consequences." Mathematical Population Studies, 12:181-182, 2005
"Over 750,000 claimants have filed suit ... for illnesses and deaths related to exposure to asbestos, and at least 65 companies had been driven to bankruptcy; these numbers continue to grow. ... This work led to substantial advances in the art of forecasting the number, timing, and nature of new claims. The authors present a lucid explanation of these advances and a description of how the matters in litigation have been settled. The presiding judge, Jack Weinstein, has contributed an informative preface ... ." (J.C. Bailar, Short Book Reviews Publication of the International Statistical Institute, Vol. 25 (1), 2005)
"Demographers Eric Stallard, Kenneth Manton and Joel Cohen use a risk assessment framework to estimate the numbers of claims expected during the period between 1990 and 2049 for asbestos-related disease among men exposed to ... asbestos products. ... Forecasting Product Liability Claims is notable for its illustration of the possibility of using epidemiologic and demographic methods to develop models for broad policy purposes. ... It is formula-rich and dense in its description of data sources and the machinery of the models, as it should be." (Jonathan M. Samet, Science-AAAS, May, 2006)
"This book summarizes the statistical models for projecting the number, timing, and nature of future claims, and it discusses how these predictions are used in developing a fair and equitable distribution of insufficientfunds. ... This book provides a fascinating account of how predication models are used to solve a very-real problem. It makes wonderful reading for statisticians interested in prediction problems, epidemiologists, actuaries, and lawyers involved in product liability suits and having to predict the number of possible litigants." (Johannes Ledolter, Zentralblatt MATH, Vol. 1099 (1), 2007)
| Overview | p. 1 |
| Introduction | p. 1 |
| Asbestos and Health | p. 1 |
| History of Asbestos | p. 4 |
| Epidemiological Discovery | p. 5 |
| Johns-Manville Corporation | p. 6 |
| Manville Trust | p. 6 |
| Manville Trust Litigation | p. 7 |
| Project History | p. 9 |
| Results | p. 11 |
| Organization of Monograph | p. 14 |
| Epidemiology of Asbestos-Related Diseases | p. 17 |
| Introduction | p. 17 |
| Design Issues in Studying Occupational Exposure | p. 18 |
| Measures of Risk | p. 19 |
| Design Issues | p. 22 |
| Studies of Health Risks of Occupational Exposures | p. 24 |
| Health Risks of a Cohort of Insulation Workers Occupationally Exposed to Asbestos | p. 25 |
| A Case-Control Study of Asbestos Risks in the United States and Canada | p. 35 |
| Short-Term Amosite Exposure Among Factory Workers in New Jersey | p. 37 |
| Effects of Chrysotile Exposure Among Miners and Millers in Quebec | p. 38 |
| Mesothelioma Risks Among World War II Shipyard Workers | p. 40 |
| Effects of Asbestos Exposure Among a Cohort of Retired Factory Workers | p. 42 |
| Increases in Disease Risk Associated with Exposure to Asbestos | p. 44 |
| Effects of Fiber Type on Disease Risks | p. 52 |
| Simian Virus 40 and Mesothelioma | p. 57 |
| Forecasts Based on Direct Estimates of Exposure | p. 61 |
| Introduction | p. 61 |
| Selikoff's Study: General Description | p. 61 |
| Data | p. 61 |
| Model and Methods | p. 62 |
| Selikoff's Six Tasks | p. 62 |
| Task 1: Identify the Industries and Occupations Where Asbestos Exposure Took Place | p. 63 |
| Task 2: Estimate the Number, Timing, and Duration of Employment of Exposed Workers | p. 67 |
| Task 3: Estimate Risk Differentials Among Occupations and Industries | p. 71 |
| Task 4: Estimate Dose-Response Models for Cancer Risks | p. 74 |
| Task 5: Project Future Asbestos-Related Cancer Mortality | p. 76 |
| Task 6: Estimate and Project Deaths Due to Asbestosis | p. 76 |
| Sensitivity of Selikoff's Projections | p. 79 |
| Alternative Projections of Health Implications | p. 81 |
| Forecasts Based on Indirect Estimates of Exposure | p. 89 |
| Introduction | p. 89 |
| Background | p. 89 |
| Walker's Study: General Description | p. 93 |
| Data | p. 93 |
| Model and Methods | p. 94 |
| Walker's Five Tasks | p. 94 |
| Task 1: Determine the Effective Number of Past Asbestos Workers | p. 95 |
| Task 2: Project Mesothelioma Incidence | p. 112 |
| Task 3: Project Lung Cancer Incidence | p. 115 |
| Task 4: Estimate Current and Future Asbestosis Prevalence | p. 119 |
| Task 5: Estimate the Amount of Asbestos-Related Disease Likely to Occur in Women | p. 124 |
| Asbestos-Related Disease Projections by Other Authors | p. 125 |
| Conclusions | p. 127 |
| Uncertainty in Forecasts Based on Indirect Estimates | p. 129 |
| Introduction | p. 129 |
| Qualitative Sources of Uncertainty in Walker's Projections | p. 129 |
| Uncertainties in Either Direction | p. 130 |
| Why Walker's Projections May Be Too Low | p. 132 |
| Why Walker's Projections May Be Too High | p. 133 |
| Sensitivity Analysis of Walker's Projections | p. 134 |
| Results for Single Parameters | p. 138 |
| Results for All Variables Jointly | p. 139 |
| Summary of Uncertainty Results | p. 142 |
| Further Sensitivity Analysis of Walker's Mesothelioma Projections | p. 143 |
| Projection Methodology | p. 145 |
| Alternative Scenarios | p. 147 |
| Results | p. 149 |
| Conclusions | p. 152 |
| Updated Forecasts Based on Indirect Estimates of Exposure | p. 155 |
| Introduction | p. 155 |
| Factors Considered | p. 155 |
| Assumptions | p. 160 |
| First-Stage Calibration: Overview | p. 165 |
| Data Preparation | p. 169 |
| Step 1: Nonmesothelioma Mortality Rates | p. 169 |
| Step 2: National Estimates of Mesothelioma Incidence Counts | p. 172 |
| Step 3: Distribution of Age and Date at Start of Asbestos Exposure for Mesothelioma Incidence Among Manville Trust Claimants | p. 174 |
| Step 4: Normalization of Exposure | p. 189 |
| Step 5: Intensity of Exposure | p. 190 |
| Model Estimation | p. 191 |
| Step 6: Stratification of National Estimates of Mesothelioma Incidence Counts, by Level of Asbestos Exposure | p. 191 |
| Step 7: Estimation of the IWE Population Exposed to Asbestos Prior to 1975 by Level of Asbestos Exposure | p. 192 |
| Step 8: Adjustments to Exposure During 1955-1974, by Level of Asbestos Exposure | p. 198 |
| Step 9: Adjustments to Reflect Improvements in the Workplace During 1960-1974, by Level of Asbestos Exposure | p. 198 |
| Step 10: Renormalization by Level of Asbestos Exposure | p. 199 |
| Model Projection | p. 200 |
| Step 11: Forward Projection of the At-Risk IWE Population by Level of Asbestos Exposure | p. 202 |
| Step 12: Forward Projection of Mesothelioma Incidence by Level of Asbestos Exposure | p. 202 |
| Nonparametric Hazard Modeling of Claim Filing Rates: CHR Model | p. 208 |
| Step 1: Distribution of 1990-1994 Claims by Attained Age, TSFE, and Disease/Injury | p. 208 |
| Step 2: Estimation of Claim Hazard Rates by Attained Age, TSFE, and Disease/Injury | p. 209 |
| Step 3: Claim Projections | p. 213 |
| Uncertainty in Updated Forecasts | p. 217 |
| Introduction | p. 217 |
| Analysis S1: Constant Age-Specific Claim Runoff | p. 222 |
| Analysis S2: Ratio Estimation of Nine Asbestos-Related Diseases - PTS Model | p. 223 |
| Analysis S3: Parametric Claim Hazard Rate Model | p. 224 |
| Analysis S4: Mesothelioma Incidence Function | p. 229 |
| Sensitivity to the b Parameter | p. 232 |
| Sensitivity to the k Parameter | p. 233 |
| Analysis S5: Adjustments to the IWE Exposed Population | p. 235 |
| Analysis S6: National Mesothelioma Incidence Counts | p. 236 |
| Analysis S7: Nonmesothelioma Mortality Rates | p. 237 |
| Analysis S8: Excess Mortality Among Insulation Workers | p. 239 |
| Analysis S9: Decline in Claim Filing Rates | p. 240 |
| Overall Sensitivity: Analyses S1-S9 | p. 241 |
| Analysis S10: Manville Trust Calibrations | p. 247 |
| Conclusions | p. 249 |
| Forecasts Based on a Hybrid Model | p. 251 |
| Introduction | p. 251 |
| Model Overview | p. 252 |
| First Stage | p. 252 |
| Second Stage | p. 254 |
| Data Preparation | p. 255 |
| Step 1: Nonmesothelioma Mortality Rates | p. 255 |
| Step 2: Occupation Groups with Significant Asbestos Exposure | p. 256 |
| Step 3: Distribution of Mesothelioma Claim Counts 1990-1994 by Attained Age at the Time of Claim and TSFE | p. 257 |
| Step 4: Distribution of Mesothelioma Claim Counts by Age at Start of Exposure and Date of First Exposure | p. 270 |
| Step 5: Normalization of Exposure | p. 273 |
| Model Estimation | p. 273 |
| Step 6: Estimation of the OSHA Model for Mesothelioma | p. 273 |
| Step 7: Estimation of the Population Exposed to Asbestos Prior to 1975 | p. 284 |
| Model Projection | p. 288 |
| Step 8: First-Stage Calibration | p. 288 |
| Step 9: Forward Projection of Mesothelioma Mortality | p. 288 |
| Second Stage: CHR Forecasting Model | p. 290 |
| Step 1: Distribution of Disease-Specific Claim Counts for 1990-1994 by Attained Age and TSFE | p. 290 |
| Step 2: Second-Stage Calibration | p. 290 |
| Step 3: At-Risk Population Projections | p. 294 |
| Step 4: Claim Projections | p. 298 |
| Conclusions | p. 308 |
| Uncertainty in Forecasts Based on a Hybrid Model | p. 311 |
| Introduction | p. 311 |
| Impact of Claim Filing Rules | p. 313 |
| Baseline Model: SDIS Criterion | p. 314 |
| Analysis S1: Validated Disease | p. 315 |
| Analysis S2: Multiple Diseases | p. 320 |
| Analysis S3: CHR Smoothing | p. 325 |
| Analysis S4: Exposure Smoothing | p. 327 |
| Analysis S5: Weibull k Parameter | p. 328 |
| Analysis S6: Relative Risks of Mesothelioma | p. 330 |
| Analysis S7: Duration of Exposure | p. 332 |
| Overall Sensitivity: Analyses S1-S7 | p. 334 |
| Conclusions | p. 336 |
| Conclusions and Implications | p. 345 |
| Introduction | p. 345 |
| Data | p. 347 |
| Comparisons of Original and Updated Data | p. 350 |
| Comparisons of Actual and Projected Numbers of Claims | p. 354 |
| Health and Vital Statistics Data, 1990-1999 | p. 359 |
| Conclusions | p. 374 |
| References | p. 377 |
| Index | p. 389 |
| Table of Contents provided by Publisher. All Rights Reserved. |
ISBN: 9780387949871
ISBN-10: 0387949879
Series: Statistics for Biology and Health
Published: 25th October 2004
Format: Hardcover
Language: English
Number of Pages: 428
Audience: Professional and Scholarly
Publisher: Springer Nature B.V.
Country of Publication: US
Dimensions (cm): 23.5 x 15.88 x 3.18
Weight (kg): 0.75
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