Falk Symposium

By: M. P. Manns (Editor), J. Spicak (Editor), E. -F Stange (Editor)

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Hardcover | 30 June 2004

At a Glance

Hardcover
332 Pages

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24.77 x 16.51 x 2.54

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This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Pre-Clinical Medicine & Basic Sciences Physiology Gastroenterology

List of Principal Contributors	p. ix
Preface	p. xiii
Immunopathogenesis and Liver Diseases: Basic Principles
The liver as an immune organ	p. 3
Immunogenetics of liver disease	p. 8
Lipotoxicity and apoptosis in non-alcoholic fatty liver disease	p. 30
Fibrogenesis, hepatic stellate cells and the immune system	p. 36
Molecular characterization of autoantigens in autoimmune liver diseases	p. 42
Immune mechanisms of viral clearance and pathogenesis of hepatitis C	p. 57
Immune aspects of pathogenesis of alcoholic liver disease	p. 72
Aetiology of primary biliary cirrhosis	p. 78
Autoimmune hepatitis and overlap syndromes	p. 92
Immunopathogenesis and Liver Diseases: Clinical Implications
Primary sclerosing cholangitis	p. 111
Immunological mechanisms of liver allograft rejection	p. 122
Recurrence of autoimmune liver disease after liver transplantation	p. 128
Human hepatic stem cells - potential for the future	p. 144
Mucosal immunity, intestinal microflora and inflammatory bowel disease	p. 152
Immunopathological Mechanisms of Gut Inflammation
Genes and immunopathology	p. 171
Defensins, innate immunity and the pathogenesis of inflammatory bowel disease	p. 172
Progress of knowledge of immunopathogenesis in coeliac disease	p. 178
Impact of immunodeficiency on immunological homeostasis in the gut	p. 180
Immunopathology of the Gut: Clinical Aspects
Pathological versus clinical differential diagnosis in inflammatory bowel disease	p. 213
Refractory sprue - what it is and what to do	p. 215
Collagenous and lymphocytic colitis: distinct disorders or part of the spectrum of inflammatory bowel disease?	p. 219
Predictive factors of the course and therapeutic response in inflammatory bowel disease	p. 234
Therapeutic Consequences of Immunopathological Processes in Inflammatory Bowel Disease
Efficacy and limits of immunomodulators in inflammatory bowel disease: azathioprine, 6-mercaptopurine, methotrexate and mycophenolate mofetil	p. 249
Does 6-thioguanine therapy represent a new promising therapeutic modality?	p. 261
Anti-tumour necrosis factor therapy in clinical practice: what is advance and what is not?	p. 267
New possibilities in anticytokine therapy for inflammatory bowel disease	p. 271
Medical therapy of inflammatory bowel disease: current state and perspectives in the future	p. 280
Index	p. 299
Table of Contents provided by Rittenhouse. All Rights Reserved.

Falk Symposium

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Hardcover

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