Epilepsy

Animal and Human Correlations

By: David W. McCandless

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Hardcover | 1 November 2011

At a Glance

Hardcover
550 Pages

Dimensions(cm)
23.5 x 15.88 x 3.81

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$372.90

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The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the "success" rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.

Industry Reviews

"This is a comprehensive text and atlas on animal and human studies of Epilepsy. ... I highly recommend this book to the following audiences: students, fellows, researchers, neurologists, neurosurgeons, and undergraduates." (Joseph J. Grenier, Amazon.com, September, 2015)

"For the clinical neurologists and epileptologists dedicated to the care of children and adults affected with epilepsy, a concise book like Epilepsy ... is a good attempt to become a source for those seeking rapid immersion in the essentials of translational epilepsy research that have tried to explain those critical aspects of epileptogenesis that involve acquired and developmental seizures. ... it is a good foundation for those looking for a quick initial reference, which may not be available in rapidly accessible vast internet sources." (Luis E. Bello-Espinosa, The Canadian Journal of Neurological Sciences, Vol. 40 (1), January, 2013)

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