Dekker Agropedia Collection

THE ROLE OF T-LYMPHOCYTES IN SKIN BIOLOGY - Michael P. Schen; A Brief View on T-Cells in the Immune System; Cutaneous Recruitment - The Bare Essentials; Tethering and Rolling - The First Steps of Leukocyte Extravazation; Lymphocyte Extravazation: Teamwork of Chemokines and Adhesion Molecules; Epidermal Localization: The Endpoint of a Long Journey; Psoriasis a Model Disease For Studying Cutaneous T-Cell Recruitment; THE PROCESS OF LYMPHOCYTE RECRUITMENT - John M. Hwang and Paul Kubes; The Multi-Step Paradigm; Tethering And Rolling; Selectins And Their Receptors; Selectin Signaling; Firm Adhesion; Chemokines and Chemokine Receptors; Integrins and Their Receptors; Affinity and Avidity Modulation; Transendothelial Migration; Cell Spreading And Locomotion; Cell Junctions; Chemotaxis; LYMPHOCYTE HOMING TO THE SKIN - Takako Hirata, Barbara C. Furie, and Bruce Furie; Adhesion Molecules and the Skin-Specific Migration of Lymphocytes; Rolling Receptors on Lymphocytes and Endothelium; Role of Glycosyltransferases and Sulfotransferases in Selectin Lignad Formation; Adhesion Molecules Mediating Firm Adhesion of Lymphocytes; Adhesion Molecules in Transmigration of Lymphocytes; Dermal Localization of Lymphocytes; Epidermal Localization of Lymphocytes; Chemokines and Skin-Specific Migration of Lymphocytes; Chemokines in Lymphocyte Trafficking; Chemokine Smediating Transition From Rolling to ArrestC; hemokines in Transmigration of Lymphocytes; Chemokines and Lymphocyte Migration Within the SkinIN VITRO TECHNIQUES TO INVESTIGATE LYMPHOCYTE EXTRAVAZATION - Judith W. Calderwood and Heinfried H. Radeke; Chemokines Activate Adhesion of Lymphocytes; Binding to Cell-Free Matrix and Adhesion Molecules: Static Adhesion Assays; Chemokines Regulate Cell-Cell Interaction: Binding of Immune Cells to EC and Other Tissue Cells Including the Stamper-Woodruff Assay; Determination of Chemotaxis and Chemokinesis; Single Cell Tracking; Wound Healing Assay; Variations of a Classical Theme: From Boyden to High-Thru Put Chemotaxis Assays; Transendothelial Migration (Tem) Under Static Conditions and Migration to Multiple Chemokine Gradients Imprinted in Inflamed Matrices; Tethering, Adhesion and Migration Under Flow Conditions; Selectin-Dependent Rolling; Integrins, Firm Adhesion and Spreading Under Flow Conditions; IN VIVO METHODS TO STUDY LYMPHOCYTE HOMING TO THE SKIN - Ralf J. Ludwig, Wolf-Henning Boehncke; Intravital Microscopy; Rationale for the Use of Intravital Microscopy; Extravazation of Endogenous Lymphocytes; Extravazation of Injected Lymphocytes; Microscope and Recording Equipment; Data Evaluation; Animal Models; Rationale For the Use of Animal Models; Cutaneous Inflammation in Wild-Type Animals; Cutaneous Inflammation in Genetically Modified Mice; Cutaneous Inflammation in Xenogeneic Skin Transplantation ModelsDrug Discovery Using Animal Models; CUTANEOUS T-LYMPHOCYTIC INFILTRATES IN SKIN PATHOLOGY - Richard Groves; Inflammatory Skin Diseases; Eczema; Psoriasis; Lichen Planus; Cutaneous Organ-Specific Autoimmune Disease: Alopecia Areata and Vitiligo; Cutaneous Malignancies; Non-Melanoma