Comparative Genomics : International Workshop, Recomb-CG 2008, Paris, France, October 13-15, 2008, Proceedings - Craig Nelson

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Comparative Genomics

International Workshop, Recomb-CG 2008, Paris, France, October 13-15, 2008, Proceedings

By: Craig Nelson (Editor), StÃ©phane Vialette (Editor)

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Paperback | 6 October 2008

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Over the last decade great investments have been made in the acquisition of enormous amounts of gene sequence data from a diverse collection of org- isms. Realizing the full potential of these investments will require the continued development of computational tools for comparative genomics and the intel- gent application of these tools to address biologically relevant questions. The RECOMB Workshop on Comparative Genomics (RECOMB-CG) is devoted to bringingtogetherscientistsworkingonallaspectsofcomparativegenomics,from the development of new computational approaches to genome sequence analysis andcomparison,to the genome-wideapplicationofcomputationaltools to study the evolutionary dynamics of prokaryotic and eukaryotic genomes. This volume contains the 19 papers presented at the 6th Annual RECOMB- ´ CG workshop held during October 13-15 at the Ecole Normale Sup´ erieure, in Paris, France. The papers selected for presentation and published in these p- ceedings were selected from 48 submissions from scientists around the world. Each paper was reviewed by at least three members of the Program Committee in a stringent and thoughtful peer-review process.

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Non-Fiction Science Biology, Life Sciences Life Sciences in General Genetics excluding Medical Computing & I.T.Computer Programming & Software Development Algorithms & Data Structures Computer Science Mathematical Theory of Computation Mathematics Molecular Biology

Science in General

Algorithms for Exploring the Space of Gene Tree/Species Tree Reconciliations	p. 1
Limitations of Pseudogenes in Identifying Gene Losses	p. 14
Duplication Mechanism and Disruptions in Flanking Regions Influence the Fate of Mammalian Gene Duplicates	p. 26
Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evolution	p. 40
Discovering Local Patterns of Co-evolution	p. 55
Ancestral Reconstruction by Asymmetric Wagner Parsimony over Continuous Characters and Squared Parsimony over Distributions	p. 72
An Alignment-Free Distance Measure for Closely Related Genomes	p. 87
Gene Team Tree: A Compact Representation of All Gene Teams	p. 100
Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer	p. 113
An Evolutionary Study of the Human Papillomavirus Genomes	p. 128
An Algorithm for Inferring Mitogenome Rearrangements in a Phylogenetic Tree	p. 143
Perfect DCJ Rearrangement	p. 158
Sorting Genomes with Insertions, Deletions and Duplications by DCJ	p. 170
A Fast and Exact Algorithm for the Median of Three Problem-A Graph Decomposition Approach	p. 184
A Phylogenetic Approach to Genetic Map Refinement	p. 198
Sorting Cancer Karyotypes by Elementary Operations	p. 211
On Computing the Breakpoint Reuse Rate in Rearrangement Scenarios	p. 226
Hurdles Hardly Have to Be Heeded	p. 241
Internal Validation of Ancestral Gene Order Reconstruction in Angiosperm Phylogeny	p. 252
Author Index	p. 265
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Comparative Genomics

International Workshop, Recomb-CG 2008, Paris, France, October 13-15, 2008, Proceedings

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