Brain Norepinephrine

Neurobiology and Therapeutics

By: Gregory A. Ordway (Editor), Michael A. Schwartz (Editor), Alan Frazer (Editor)

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Paperback | 13 September 2012

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662 Pages

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This book was first published in 2007. Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects. Noradrenergic drugs have been proven effective for depression and ADHD, and new disease indications are being identified. A team of experts provides the reader with a thorough understanding of the anatomy, physiology, molecular biology, pharmacology and therapeutics of norepinephrine in the brain, including an extensive review of the role of norepinephrine in brain diseases. The book is divided into four sections: the basic biology of norepinephrine; the role that norepinephrine plays in behavior; evidence of norepinephrine's role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs in the treatment of psychiatric and neurological disorders.

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You Can Find This Book In

Non-Fiction Medicine Other Branches of Medicine Psychiatry Clinical Psychology Clinical & Internal Medicine Neurology & Clinical Neurophysiology Science Biology, Life Sciences Life Sciences in General Neurosciences Medicine in General

Health Systems & Services Mental Health Services

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Published: 15th February 2007

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Introduction: Revision of an Old Transmitter
The Neurobiology of Norepinephrine
Neuroanatomical and chemical organization of the locus coeruleus
Interactions of norepinephrine with other neurotransmitter systems: anatomical basis and pharmacology
Receptors for norepinephrine and signal transduction pathways
Regulation of gene transcription in the central nervous system by norepinephrine
The norepinephrine transporter and regulation of synaptic transmission
Norepinephrine and Behavior
Role of the locus coeruleus-norepinephrine system in arousal and circadian regulation of the sleep wake cycle
Locus coeruleus and regulation of behavioral flexibility and attention: clinical implications
Norepinephrine and long-term memory function
Norepinephrine and stress
The Biology of Norepinephrine in CNS Pathology
Animal models of psychopathology: focus on norepinephrine
Neuropathology of central norepinephrine in psychiatric disorders: postmortem research
Norepinephrine in mood disorders
Noradrenergic pathology and pain
Norepinephrine in cognitive disorders
Norepinephrine in neurological disorders
Genetics of noradrenergic neurobiology
Psychopharmacology of Norepinephrine
Actions of antidepressant and other drugs on norepinephrine systems
The clinical role of norepinephrine antidepressants in depression and anxiety disorders
Norepinephrine in attention deficit hyperactivity disorder
Psychopharmacology of norepinephrine in eating disorders
Role of norepinephrine in substance abuse
Table of Contents provided by Publisher. All Rights Reserved.

Brain Norepinephrine

Neurobiology and Therapeutics

At a Glance

Paperback

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How to return your order

Defective items

You Can Find This Book In

Other Editions and Formats

Hardcover

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