Biochemical Oscillations and Cellular Rhythms

The Molecular Bases of Periodic and Chaotic Behaviour

By: Albert Goldbeter, M. J. Berridge (Foreword by), Goldbeter

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Paperback | 2 June 1997

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632 Pages

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23.39 x 15.6 x 3.23

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This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. The approach rests on the analysis of theoretical models closely related to experimental observations. Among the main rhythms considered are glycolytic oscillations observed in yeast and muscle, oscillations of cyclic AMP in Dictyostelium amoebae, intracellular calcium oscillation observed in a variety of cell types, the mitotic oscillator that drives the cell division cycle in eukaryotes, pulsatile hormone signaling, and circadian rhythms in Drosophila. This book will be of interest to life scientists such as biochemists, cell biologists, chronobiologists, medical scientists and pharmacologists. In addition, it will appeal to scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and theoretical biology.

Industry Reviews

'The book beautifully illustrates the art of modelling ... The author has been studying the theory of oscillations and rhythms for 25 years and brings a great deal of experience to bear on this book ... It is an excellent read and will appeal to a wide-ranging audience, from students moving into the area to established researchers in the field, and from mathematical modellers to experimentalists in the life sciences.' Trends in Biochemical Sciences '... an extraordinarily impressive volume. I am fully confident that it will be the definitive work in this area for years to come.' Paul Rapp, Professor of Physiology, Medical College of Pennsylvania 'It really is a very impressive tome and is a superb addition to the literature. It is quite clearly going to be the reference book on oscillations.' James D. Murray, Professor of Applied Mathematics and Mathematical Biology, University of Washington, Seattle

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Introduction
Glycolytic Oscillations
Oscillatory enzymes: simple periodic behaviour in an allosteric model for glycolytic oscillations
From Simple to Complex Oscillatory Behaviour
Birhythmicity: coexistence between two stable rhythms
From simple periodic behaviour to complex oscillations, including bursting and chaos
Oscillations Of Cyclic Amo In Dictyostelium Cells
Models for the periodic synthesis and relay of camp signals in Dictyostelium discoideum amoebae
Complex oscillations and chaos in the camp signalling system of Dictyostelium
The onset of camp oscillations in Dictyostelium as a model for the ontogenesis of biological rhythms
Pulsatile Signalling In Intercellular Communication
Function of the rhythm of intercellular communication in Dictyostelium. Link with pulsatile hormone secretion
Calcium Oscillations
Oscillations and waves of intracellular calcium
The Mitotic Oscillator
Modelling the mitotic oscillator driving the cell division cycle
Circadian Rhythms
Towards a model for circadian oscillations in the Drosophila period protein (PER)
Conclusions and perspectives
References
Table of Contents provided by Publisher. All Rights Reserved.

Biochemical Oscillations and Cellular Rhythms

The Molecular Bases of Periodic and Chaotic Behaviour

At a Glance

Paperback

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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