Venous Thrombosis

From Genes to Clinical Medicine

By: D.N. Cooper, M. Krawczak

Write A Review

eText | 6 December 2024 | Edition Number 1

At a Glance

Format
ePUB

eText

$396.00

or 4 interest-free payments of $99.00 with

Instant online reading in your Booktopia eTextbook Library *

Why choose an eTextbook?

Instant Access *

Purchase and read your book immediately

Read Aloud

Listen and follow along as Bookshelf reads to you

Study Tools

Built-in study tools like highlights and more

* eTextbooks are not downloadable to your eReader or an app and can be accessed via web browsers only. You must be connected to the internet and have no technical issues with your device or browser that could prevent the eTextbook from operating.

Thrombotic disease is a major cause of death and disablement in Western society. The most common causes is an inherited defect in one of the many genes encoding a protein which is involved in clotting, It's regulation or the process of clot dissolution, Fibrinolysis.

Venous Thrombosis: from genes to clinical medicine, presents our current knowledge of potentially prothrombotic protein at modalities, together with the clear and concise views of the roles these proteins play in haemostasis, and the use of molecular techniques in the analysis and diagnosis of inherited defects. Each chapter describes a specific protein deficiency, with information on protein structure, function and biochemistry, gene structure and expression, as well as epidemiological and molecular genetic aspects of the deficiency state.

This multifaceted approach aims to examine the possible causes of venous thrombosis, to explain the underlying molecular defects, and to explore the genotype-phenotype relationship in this complex multi gene disorder. The potential roles of both aesthetic interactions and environmental risk factors are also discussed. This book will be of value to haematologists, genetic counsellors and clinical geneticists.