The Gene Wars

Science, Politics, and the Human Genome

By: Robert Cook-Deegan

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Paperback | 1 January 1995 | Edition Number 1

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420 Pages

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2.36 x 1.57 x 0.28

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The Human Genome Project, the most ambitious biological research program ever undertaken, was born in controversy. Heralded by its more enthusiastic proponents as a quest for the 'Holy Grail of biology' - and the key, ultimately, to the treatment of a variety of hereditary diseases - it has as its initial goal the mapping of all the genes in the entire three-billion-letter genetic code embodied in the DNA of a typical human cell. A major factor in the counterarguments of its opponents: its projected cost, estimated to run into the billions of dollars, spread over 10-20 years. In this firsthand account of the protracted struggle to launch the genome project, a close observer of that process - and sometime participant in it - unravels the tangled scientific and political threads of the story, relying on primary documents gathered even as events unfolded, supplemented by interviews with all the main actors - including the controversial first head of the National Institutes of Health genome effort, Nobel laureate James D. Watson. The result is an absorbing case study in the politics of modern science - focused in this case on a project with far-reaching medical and social implications.

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Preface	p. 9
The Scientific Foundation
Why Genetics?	p. 13
Mapping Our Genes	p. 29
Of Yeasts and Worms	p. 48
Sequence upon Sequence	p. 56
Origins of the Genome Project
Putting Santa Cruz on the Map	p. 79
Gilbert and the Holy Grail	p. 85
Genes and the Bomb	p. 92
Early Skirmishes	p. 107
The Support Structure
The Odd Legacy of Howard Hughes	p. 117
The NAS Redefines the Project	p. 125
The NIH Steps Forward	p. 135
Tribes on the Hill	p. 148
Honest Jim and the Genome	p. 161
Genome Gone Global
First Stirrings Abroad	p. 187
Japan: A Special Case	p. 213
Ethical, Legal, and Social Issues
A New Social Contract	p. 231
Bioethics in Government	p. 256
Wizards of the Information Age	p. 283
DNA Goes to Court	p. 299
Exodus: The End of the Beginning	p. 326
Epilogue	p. 341
Chronology	p. 353
Acknowledgments	p. 357
References and Notes	p. 366
Index	p. 405
Table of Contents provided by Blackwell. All Rights Reserved.

The Gene Wars

Science, Politics, and the Human Genome

At a Glance

Paperback

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How to return your order

Defective items

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