The Epididymis

From Molecules to Clinical Practice : A Comprehensive Survey of the Efferent Ducts, the Epididymis and the Vas Deferens

By: Bernard Robaire (Editor), Barry Hinton (Editor)

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Hardcover | 31 December 2001

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Hardcover
596 Pages

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24.77 x 16.51 x 4.45

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Since the late 1960s, there has been an acceleration of research focused on understanding how the efferent ducts, the epididymis, and the vas deferens function with respect to the maturation and storage of spermatozoa and as hormone dependent tissues. Another major interest in the epididymis is that it is an attractive target for the development of male contraceptives. There are well over 16,000 peer reviewed articles in the literature on these tissues, their structure, gene expression, protein synthesis and function. Regular international meetings have been initiated that are dedicated to this field. Thus, there is an urgent need for a comprehensive reference volume that spans every facet of epididymal biology, from historical background to the most current results, from basic cell and molecular biology to clinical issues. Well-established experts from every part of the world have contributed to this volume. By necessity, each author was given page limitations so that many topics are not dealt with exhaustively. Whenever possible, references to more comprehensive discussion of specific topics are included.

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The Testicular Excurrent Duct System: A Historical Outlook	p. 1
Evolution of the Vertebrate Epididymis	p. 11
Innervation and Vasculature of the Excurrent Duct System	p. 35
The Epithelium of the Excurrent Duct System
The Efferent Ductules: Structure and Functions	p. 49
Epididymal Cell Types and Their Functions	p. 81
Cellular Interactions and the Blood-Epididymal Barrier	p. 103
Formation of the Epididymal Fluid Microenvironment	p. 119
Necessity's Potion: Inorganic Ions and Small Organic Molecules in the Epididymal Lumen	p. 131
Protein Secretion in the Epididymis	p. 151
Gene Expression and Epididymal Function	p. 169
Specific Gene Expression in the Human and Non-Human Primate Epididymis	p. 201
Interactions of the Immune System and the Epididymis	p. 219
The Structural Organization and Functions of the Epithelium of the Vas Deferens	p. 233
Development and Aging
The Development of the Epididymis	p. 251
Homeobox Genes and the Male Reproductive System	p. 269
Aging of the Epididymis	p. 285
Hormonal Regulation and Effects of Toxicants
Androgenic Regulation of the Structure and Functions of the Epididymis	p. 297
The Role of Estrogens in the Endocrine and Paracrine Regulation of the Efferent Ductules, Epididymis and Vas Deferens	p. 317
Retinoids and Epididymal Function	p. 339
Actions of Toxicants on the Structure and Function of the Epididymis	p. 353
Changes in Spermatozoa During Epididymal Transit
Structural Differentiation of Spermatozoa During Post-Testicular Maturation	p. 371
Changes in Sperm Proteins During Epididymal Maturation	p. 389
Plasma Membrane Composition and Organisation During Maturation of Spermatozoa in the Epididymis	p. 405
Acquisition and Development of Sperm Motility upon Maturation in the Epididymis	p. 417
Active Oxygen in Spermatozoa During Epididymal Transit	p. 435
Novel Technological Approaches
Cell and Organ Epididymal Cultures	p. 449
Smart Use of Computer-Aided Sperm Analysis (CASA) to Characterize Sperm Motion	p. 459
Clinical Considerations
Management of Epldidymal Dysfunction: Correlation with Basic Physiology	p. 473
The Epididymis as a Target for Male Contraception	p. 483
Consequences of Obstruction on the Epididymis	p. 503
Infertility, ICSI, and the Epididymis	p. 523
Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System	p. 533
Cancer of the Epididymis	p. 555
Author Index	p. 563
Subject Index	p. 565
Table of Contents provided by Syndetics. All Rights Reserved.

The Epididymis

From Molecules to Clinical Practice : A Comprehensive Survey of the Efferent Ducts, the Epididymis and the Vas Deferens

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

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Paperback

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