Systems Metabolic Engineering

By: Christoph Wittmann (Editor), Sang Yup Lee (Editor)

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Hardcover | 16 June 2012

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Hardcover
400 Pages

Dimensions(cm)
24.77 x 16.51 x 2.54

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Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production.

Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story - from genomes and networks via discovery and design to industrial implementation practises.

This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

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Genome-Scale Network Modeling	p. 1
Kinetic Modeling of Metabolic Networks	p. 25
Design of Superior Cell Factories Based on Systems Wide Omics Analysis	p. 57
Technologies for Biosystems Engineering	p. 83
Systems Metabolic Engineering of Escherichia coli for Chemicals, Materials, Biofuels, and Pharmaceuticals	p. 117
Systems Metabolic Engineering of Corynebacterium glutamicum for Biobased Production of Chemicals, Materials and Fuels	p. 151
Towards a Synthetic Biology of the Stress-Response and the Tolerance Phenotype: Systems Understanding and Engineering of the Clostridium acetobutylicum Stress-Response and Tolerance to Toxic Metabolites	p. 193
Model-Based Design of Superior Cell Factory: An Illustrative Example of Penicillium chrysogenum	p. 221
Bridging Omics Technologies with Synthetic Biology in Yeast Industrial Biotechnology	p. 271
Design of Superior Cell Factories for a Sustainable Biorefinery By Synthetic Bioengineering	p. 329
Systems-Level Analysis of Cancer Metabolism	p. 349
Index	p. 383
Table of Contents provided by Ingram. All Rights Reserved.

Systems Metabolic Engineering

At a Glance

Hardcover

Shipping

How to return your order

Defective items

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