| Preface: Manic Depression or Bipolar Disorder? | p. xv |
| Acknowledgments | p. xix |
| Dimensions of Manic-Depressive Illness | p. 1 |
| How Many People in the United States Have Manic-Depressive Illness? | p. 2 |
| How Many People Are Being Treated? | p. 4 |
| Do Some Groups Have More Than Others? The Hutterites and the Amish | p. 5 |
| What Is the Prevalence of Manic-Depressive Illness in Other Countries? | p. 8 |
| Has Manic-Depressive Illness Always Existed? | p. 9 |
| Is Manic-Depressive Illness Increasing? | p. 13 |
| What Is the Cost of Manic-Depressive Illness? | p. 15 |
| The Inner World: Mania and Depression From the Inside | p. 19 |
| Mania | p. 21 |
| Depression | p. 31 |
| Mixed States | p. 38 |
| Awareness of Illness | p. 41 |
| The Outer Worlds: Manic-Depressive Illness Defined | p. 45 |
| Official Definitions | p. 45 |
| Are Unipolar Depression and Manic-Depressive Illness One Disease or Two? | p. 52 |
| Where Does Manic-Depressive Illness End and Normal Mood Swings Begin? | p. 56 |
| What Is the Relationship of Manic-Depressive Illness to Schizoaffective Disorder and Schizophrenia? | p. 57 |
| Conditions Sometimes Confused with Manic-Depressive Illness | p. 63 |
| Mania Caused by Street Drugs | p. 63 |
| Mania Caused by Prescription, Over-the-Counter, and Herbal medications | p. 67 |
| Mania Caused by Infections | p. 70 |
| Mania Caused by Head Injuries | p. 72 |
| Mania Associated with Other Brain Disorders | p. 74 |
| Mania Associated with Other Illnesses | p. 75 |
| What Does Secondary Mania Tell Us About Brain Localization? | p. 76 |
| Manic-Like Behavior in Culture-Bound Syndromes | p. 77 |
| What Is an Adequate Diagnostic Workup? | p. 78 |
| Risk Factors for Developing Manic-Depressive Illness | p. 83 |
| Winter Birth | p. 84 |
| Summer Onset | p. 86 |
| Urban Birth | p. 87 |
| Pregnancy and Birth Complications | p. 88 |
| Prenatal Famine | p. 89 |
| Prenatal Exposure to Influenza | p. 89 |
| Severe Stressors in Childhood | p. 90 |
| Social Class | p. 92 |
| Onset, Course, and Outcome | p. 95 |
| Factors Affecting Course | p. 96 |
| Rapid Cycling and Seasonal Affective Disorder | p. 98 |
| Outcomes and Their Predictors | p. 100 |
| Stress as a Risk Factor for Relapse | p. 103 |
| Causes of Death | p. 104 |
| Causes | p. 107 |
| Studies of Brain Structure | p. 108 |
| Studies of Brain Function | p. 113 |
| Genetic Studies | p. 116 |
| Neurochemical Studies | p. 121 |
| Studies of Infections and Immunological Factors | p. 126 |
| Disturbances in Body Rhythms | p. 129 |
| Endocrine Dysfunction | p. 130 |
| Kindling and Stress | p. 133 |
| Medications: Mood Stabilizers | p. 137 |
| Lithium | p. 137 |
| Valproate (Depakote, Depakene) | p. 149 |
| Carbamazepine (Tegretol) | p. 151 |
| Lamotrigine (Lamictal) | p. 154 |
| Topiramate (Topamax) | p. 157 |
| Gabapentin (Neurontin) | p. 158 |
| Calcium Channel Blockers | p. 159 |
| Essential Fatty Acids | p. 161 |
| Medications: Antidepressants, Antipsychotics, and Benzodiazapines | p. 163 |
| Antidepressants | p. 163 |
| Selective Serotonin Reuptake Inhibitors (SSRIs) | p. 164 |
| Burproprion and Other New Antidepressants | p. 167 |
| Tricyclic Antidepressants | p. 169 |
| Monoamine Oxidase Inhibitors (MAOIs) | p. 170 |
| Stimulants | p. 173 |
| Thyroid Supplementation | p. 175 |
| St. John's Wort and Other Herbal Remedies | p. 175 |
| Switch Rate | p. 176 |
| Antipsychotics | p. 177 |
| First-Generation, or Typical, Antipsychotics | p. 177 |
| Second-Generation, or Atypical, Antipsychotics | p. 180 |
| Benzodiazepines | p. 185 |
| Medications: Treatment Strategies | p. 189 |
| Treatments for the Different Phases of Manic-Depressive Illness | p. 189 |
| Acute Mania | p. 190 |
| Depression | p. 191 |
| Rapid Cycling | p. 191 |
| Maintenance Treatment | p. 192 |
| Frequently Asked Questions About Medications | p. 192 |
| Do I Really Need to Take All of These Medications? | p. 192 |
| Do I Need to Take These Medications for the Rest of My Life? | p. 193 |
| What If I Am Pregnant or Breast-Feeding? | p. 194 |
| Should Treatment Be Different for the Very Old and the Very Young? | p. 200 |
| Nonmedication Aspects of Treatment | p. 203 |
| Finding a Good Doctor | p. 203 |
| Building a Support Network | p. 206 |
| Psychotherapy | p. 207 |
| Reducing Stress | p. 212 |
| Mood Charts | p. 213 |
| Electroconvulsive Therapy | p. 214 |
| Insurance Issues | p. 215 |
| SSI and SSDI | p. 217 |
| Manic-Depressive Illness in Children and Adolescents | p. 221 |
| Clinical Aspects | p. 222 |
| Diagnostic Aspects | p. 225 |
| Treatment Aspects | p. 228 |
| Ten Special Problems | p. 233 |
| Concurrent Alcohol and Drug Abuse | p. 233 |
| Assaultive and Violent Behavior | p. 237 |
| Medication Noncompliance | p. 240 |
| Assisted Treatment | p. 244 |
| Homelessness | p. 248 |
| Arrests and Jailings | p. 251 |
| Suicide | p. 253 |
| Sex and AIDS | p. 258 |
| Confidentiality | p. 259 |
| The Seduction of Mania | p. 263 |
| Manic-Depressive Illness and Creativity | p. 267 |
| Biographical Studies of Mental Illness in Creative People | p. 269 |
| Studies of Psychiatric Illness in Living Artists | p. 272 |
| Mental Illness and Creativity in Relatives | p. 274 |
| Direct Measurements of Creativity in People with Mental Illness | p. 275 |
| The Effects of Psychotropic Medications on Creativity | p. 276 |
| Commonly Asked Questions | p. 279 |
| Should I Tell People? | p. 279 |
| What Are the Chances That Other Family Members Will Get Manic-Depressive Illness? | p. 281 |
| How Does It Affect Family Members? | p. 283 |
| How Does It Affect Siblings? | p. 286 |
| How Does It Affect Spouses? | p. 287 |
| How Does It Affect Children? | p. 288 |
| Issues for Advocates | p. 293 |
| Advocacy Organizations | p. 294 |
| Scientologists, Antipsychiatrists, and "Consumer Survivors" | p. 295 |
| Research Funding and the National Institute of Mental Health | p. 297 |
| Stigma and Public Education | p. 299 |
| Exemplary Individual Advocates | p. 301 |
| Review of Books | p. 307 |
| Selected Websites | p. 329 |
| Review of Videotapes | p. 333 |
| Useful Resources | p. 337 |
| Notes | p. 341 |
| Index | p. 379 |
| Table of Contents provided by Syndetics. All Rights Reserved. |
