Subcellular Proteomics

From Cell Deconstruction to System Reconstruction

By: Eric Bertrand (Editor), Michel Faupel (Editor)

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Hardcover | 18 July 2007

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Hardcover
416 Pages

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22.86 x 15.24 x 1.91

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This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Molecular Biology Cellular Biology Biochemistry Proteins Life Sciences in General Medicine Pre-Clinical Medicine & Basic Sciences

Acknowledgements	p. xiii
List of Contributors	p. xv
Introduction	p. xxi
Membrane Proteomics	p. 1
Keynotes on Membrane Proteomics	p. 3
Two-Dimensional BAC/SDS-PAGE for Membrane Proteomics	p. 13
Microparticles: A New Tool for Plasma Membrane Sub-cellular Proteomic	p. 21
Lipid Raft Proteomics: More than Just Detergent-Resistant Membranes	p. 35
Organelle Subproteomes	p. 49
Organelle Proteome Variation Among Different Cell Types: Lessons from Nuclear Membrane Proteins	p. 51
Synaptosome Proteomics	p. 77
Proteomic Analysis of Secreted Exosomes	p. 99
Characterization of Supramolecular Protein Complexes	p. 133
From Protein-Protein Complexes to Interactomics	p. 135
Supramolecular Signalling Complexes in the Nervous System	p. 185
Protein Networks and Complexes in Photoreceptor Cilia	p. 209
Subcellular Systems Biology	p. 237
Systems Biology and the Reconstruction of the Cell: From Molecular Components to Integral Function	p. 239
Automated, Systematic Determination of Protein Subcellular Location using Fluorescence Microscopy	p. 263
Systems Biology of the Endoplasmic Reticulum Stress Response	p. 277
Emerging Technologies in Proteomics	p. 299
Systems Nanobiology: From Quantitative Single Molecule Biophysics to Microfluidic-Based Single Cell Analysis	p. 301
Biophotonics Applied to Proteomics	p. 323
Differential Epitope Identification of Antibodies Against Intracellular Domains of Alzheimer's Amyloid Precursor Protein Using High Resolution Affinity-mass Spectrometry	p. 339
LC-Maldi MS and MS/MS - An Efficient Tool in Proteome Analysis	p. 355
Index	p. 381
Color Plates	p. 385
Table of Contents provided by Ingram. All Rights Reserved.

Subcellular Proteomics

From Cell Deconstruction to System Reconstruction

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

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