Prognostic Epigenetics

Prognostic Epigenetics, Volume Twelve presents leading chapter authors from across the globe who bring readers from basic science to clinical application. Beginning with a thorough introduction to individual variability in epigenetic processes, lab technology and research methods, the role of DNA methylation, chromatin dynamics, histone modifications, and noncoding RNAs in epigenetic prognostics, the book then explores the epigenetic mechanisms associated with particular disorder prognostics, providing clinicians and researchers with effective tools for the identification and development of biomarkers. Neurological disorders, neurodegenerative disorders, asthma, allergies, metabolic syndromes, obesity, cardiovascular disorders, cancer, infectious disease, autoimmune disorders, and more are covered.

Concluding chapters focus on the role of epigenetic biomarkers in personalized medicine, as well as next steps in research and future challenges for the field.

• Compiles all known information on prognostic epigenetics and its role in preventative medicine and drug discovery
• Covers the basic functionality of epigenetic mechanisms involved in early disease prognosis and diagnosis
• Provides tools for the identification and development of prognostic biomarkers for a wide range of diseases
• Enables clinicians, researchers and pharmacologists to improve preventative medicine and precision therapeutics
• Features chapter contributions from leading international researchers