Polymer Based Systems on Tissue Engineering, Replacement and Regeneration

By: Rui L. Reis (Editor), Daniel Cohn (Editor)

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Hardcover | 30 November 2002

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440 Pages

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25.4 x 16.51 x 2.54

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Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21^st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.

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Published: 30th November 2002

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Contributors	p. ix
Welcome Addresses
Preface	p. 3
30 Years of R&D in Portugal	p. 7
Overview on Polymeric Biomaterials and Biodegradable Polymers
Polymeric Biomaterials in Medical Systems	p. 13
Biodegradable Polymers for Orthopaedic Applications	p. 25
Polymeric Matrices for Release of Growth Factors, Hormones and Other Bioactive Agents	p. 37
Novel Systems, Hydrogels and Bone Cements
Membranes and Hydrogels in Reconstructive Surgery	p. 55
Key-Properties and Recent Advances in Bone Cements Technology	p. 69
Soy Protein-Based Systems for Different Tissue Regeneration Applications	p. 93
Characterization of Polymeric Systems and Scaffolds
In Vitro Testing of Polymeric Scaffolds	p. 113
Characterization of Degradable Polymers for Orthopedic Application: Examining Tyrosine-Derived Polycarbonates for Tissue Engineering of Bone	p. 125
Dynamic Mechanical Analysis in Polymers for Medical Applications	p. 139
Surface Modification, Functionalization and Osteoconductivity
Macromolecular Design of New Synthetic Biodegradable Medical Polymers: Functional Polyesters and Copolymers with Cell-adhesion Peptide Sequences	p. 167
Surface Treatments and Pre-Calcification Routes to Enhance Cell Adhesion and Proliferation	p. 183
Tissue Engineering and Regeneration of Bone and Cartilage
Bone Tissue Engineering Using Starch Based Scaffolds Obtained by Different Methods	p. 221
Bone Tissue Engineering by Cell Transplantation	p. 251
Cultured Bone on Biomaterial Substrates: A Tissue Engineering Approach to Treat Bone Defects	p. 265
Injectable Biodegradable Materials for Orthopaedic Tissue Engineering	p. 299
Tissue Engineering of Elastic Cartilage by Using Scaffold/Cell Constructs with Different Physical and Chemical Properties	p. 313
Craniofacial Bone Tissue Engineering Using Medical Imaging, Computational Modeling, Rapid Prototyping, Bioresorbable Scaffolds and Bone Marrow Aspirates	p. 333
Tissue Engineering and Regeneration of Other Tissues
Biodegradable Polymers as Scaffolds for Tissue Engineering and as Tissue Regeneration Inducers	p. 357
Scaffolding Arterial Tissue	p. 371
Tissue-Engineered Vascular Grafts for Small-Diameter Arterial Replacement	p. 391
Industrial and Innovation Opportunities
An Exploratory Analysis of the Determinants of Innovation in the Emerging Tissue Engineering Industry	p. 409
Index	p. 419
Table of Contents provided by Ingram. All Rights Reserved.

Polymer Based Systems on Tissue Engineering, Replacement and Regeneration

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