On Snake-Poison

Its Action and Its Antidote

By: A. Mueller

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eBook | 1 September 2025

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On Snake-Poison: Its Action and Its Antidote by Sir Joseph Fayrer is a pioneering medical treatise that delves into the complex and often deadly effects of snake venom on the human body, as well as the search for effective antidotes. Drawing on his extensive experience as a physician in British India, Fayrer meticulously documents the physiological symptoms and pathological changes caused by the bites of various venomous snakes, including cobras, kraits, and vipers. The book presents detailed case studies, experimental observations, and autopsy findings, offering a comprehensive analysis of the mechanisms by which snake-poison acts on the nervous, circulatory, and respiratory systems. Fayrer critically examines the prevailing theories of his time, challenging misconceptions and providing evidence-based insights into the nature of snake venom. He discusses the limitations of traditional remedies and evaluates the efficacy of various treatments, including ligatures, excision, cauterization, and the use of chemical antidotes. The author also explores the potential for developing a universal antidote, emphasizing the importance of prompt and appropriate medical intervention. Richly illustrated with engravings and diagrams, On Snake-Poison: Its Action and Its Antidote serves as both a scientific reference and a practical guide for medical professionals, naturalists, and anyone interested in the dangers posed by venomous snakes. Fayrer's work is notable for its rigorous methodology, clear exposition, and compassionate concern for the victims of snakebite, making it a landmark contribution to the fields of toxicology, tropical medicine, and public health.