$15 off when you spend $100 with code SPRING15 at checkout* - T&Cs apply - Limited time only
Track My Order
Help Centre
Likes
My Wish ListsLogin / Join
Booktopia
Australia's local bookstore
Get Free Shipping on orders over $79
Nuclear Pore Complexes in Genome Organization, Function and Maintenance : Biomedical and Life Sciences (R0) - Author

Nuclear Pore Complexes in Genome Organization, Function and Maintenance

By: Author

eText | 2 February 2018

At a Glance

eText

$239.00

or 4 interest-free payments of $59.75 with

 or 

Instant online reading in your Booktopia eTextbook Library *

Why choose an eTextbook?

Instant Access *

Purchase and read your book immediately

Read Aloud

Listen and follow along as Bookshelf reads to you

Study Tools

Built-in study tools like highlights and more

* eTextbooks are not downloadable to your eReader or an app and can be accessed via web browsers only. You must be connected to the internet and have no technical issues with your device or browser that could prevent the eTextbook from operating.

The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome.

on
Desktop
Tablet
Mobile

You Can Find This eBook In

Non-FictionMedicinePre-Clinical Medicine & Basic SciencesMedical GeneticsScienceBiology, Life SciencesMolecular BiologyCellular BiologyLife Sciences in GeneralGenetics excluding Medical

More in Medical Genetics

The Curse Of Lipedema - Dr. Heba Nasser

eBOOK

The Curse Of Lipedema

eBook

$8.99

Clinical Genomics : Concepts and Applications - Marcelo A. Marti

eBOOK

Clinical Genomics

Concepts and Applications

eBook

RRP $229.00

$206.13

10%
OFF
Triogeny - Teobaldo Llosa Rojas

eBOOK

Triogeny

eBook

$17.99

This product is categorised by