Mouse Genetics

1: An Introduction to Mice 1.1: Of Mice, Men, and a Woman 1.2: The Origin of Mice in Genetic Research 1.3: The New Biology and the Mouse Model 2: Town Mouse, Country Mouse 2.1: What are Mice? 2.2: Where Do Mice Come From? 2.3: The Mus Species Group and the House Mouse 2.4: Lifestyles and Adaptability of Wild House Mice 3: Laboratory Mice 3.1: Sources of Laboratory Mice 3.2: Mouse Crosses and Standard Strains 3.3: Coisogenics, Congenics, and Other Specialized Strains 3.4: Standardized Nomenclature 3.5: Strategies for Record-Keeping 4: Reproduction and Breeding 4.1: Reproductive Performance: Comparison of Inbred Strains 4.2: Germ Cell Differentiation and Sexual Maturation 4.3: Mating and Pregnancy 4.4: The Postnatal Period 4.5: Assisted Reproduction for the Infertile Cross 5: The Mouse Genome 5.1: Quantifying the Genome 5.2: Chromosomes 5.3: Genome Evolution and Gene Families 5.4: Repetitive "Non-Functional" DNA Families 5.5: Genomic Imprinting 6: Mutagenesis and Transgenesis 6.1: Classical Mutagenesis 6.2: Embryo Manipulation 6.3: Transgenic Mice Formed by Nuclear Injection 6.4: Targeted Mutagenesis and Gene Replacement 6.5: Further Uses of Transgenic Technologies 7: Mapping in the Mouse: An Overview 7.1: Genetic Maps Come in Various Forms 7.2: Mendel's Genetics, Linkage, and the Mouse 7.3: General Strategies for Mapping Mouse Loci 7.4: The Final Chapter of Genetics 8: Genetic Markers 8.1: Genotypic and Phenotypic Variation 8.2: Restriction Fragment Length Polymorphisms (RFLPs) 8.3: Polymorphisms Detected by PCR 8.4: Region-Specific Panels of DNA Markers 9: Classical Linkage Analysis and Mapping Panels 9.1: Demonstration of Linkage in the Mouse 9.2: Recombinant Inbred Strains 9.3: Interspecific Mapping Panels 9.4: Starting From Scratch With a New Mapping Project 9.5: Quantitative Traits and Polygenic Analysis 10: Non-Breeding Mapping Strategies 10.1: Linkage Maps Without Breeding 10.2: Chromosomal Mapping Tools 10.3: Physical Maps and Positional Cloning 10.4: The Human Genome Project and the Ultimate Map Appendix A: Suppliers of Mice: Appendix B: Computational Tools and Electronic Databases: Appendix C: Source Materials for Further Reading: Appendix D: Statistics: Appendix E: Glossary of Terms: