Microbiota-Brain Axis

A Neuroscience Primer

By: Foster, Heijtz

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Paperback | 23 February 2024 | Edition Number 1

At a Glance

Paperback
278 Pages

Dimensions(cm)
22.23 x 14.61 x 1.27

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Microbiota-Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct microbiota-brain research correctly and effectively, understanding the appropriate methodologies, as well as how to collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health, and neurodegeneration. The book also discusses advances in microbiota analysis tools and techniques for neuroscience related research.

Reviews the many approaches to manipulating the microbiota in animal studies-including the use of germ-free animals, antibiotics, and diet-and covers strengths and limitations of each
Outlines available microbiota research tools such as 16S sequencing and shot-gun metagenomics, and provides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics
Considers microbiota composition and function over the lifespan, discussing the influence of age, genetics, diet, and sex
Discusses clinical approach, implications, and advances, as well as potential microbiota-targeted therapies and opportunities for novel drug discovery

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