
Micro Total Analysis Systems '98
Proceedings of the uTAS '98 Workshop, held in Banff, Canada, 13-16 October 1998
By: D. Jed Harrison (Editor), Albert van den Berg (Editor)
Hardcover | 30 September 1998
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512 Pages
22.23 x 15.88 x 2.54
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This volume contains the proceedings of the Third International Symposium on Micro-Total Analysis Systems, mu-TAS '98, held on October 13-16 in Banff, Alberta, Canada. State-of-the-art invited and contributed papers presented by the world's leading mu- TAS research groups provide a highly informative picture of the growth since 1994 and of the promising future of this exciting and rapidly growing field.
| DNA Analysis with Capillary Array Electrophoresis Microplates | p. 1 |
| Continuous Flow PCR on a Chip | p. 7 |
| Advances in Integrated Genetic Analysis | p. 11 |
| Photo-Polymer Microchannel Technologies and Applications | p. 17 |
| Parallel Separations in Microfabricated Channels with Capillary Electrophoretic Sample Introduction | p. 23 |
| Novel Interconnection and Channel Technologies for Microfluidics | p. 27 |
| A [mu]-TAS Based on Microdialysis for On-line Monitoring of Clinically Relevant Substances | p. 31 |
| Microdevices for Electrospray Mass Spectrometry | p. 35 |
| Cell Sorting in Microfluidic Systems | p. 39 |
| Electrohydrodynamic Pumps for High-Density Microfluidic Arrays | p. 45 |
| Electrokinetic Generation of High Pressures using Porous Microstructures | p. 49 |
| Studies of Hydrostatic Pressure Effects in Electrokinetically Driven [mu]-TAS | p. 53 |
| An Electronic Nose Based on a Micromechanical Cantilever Array | p. 57 |
| Chemical Analysis Based on Environmentally Sensitive Hydrogels and Optical Diffraction | p. 61 |
| Mass-Sensing Multianalyte Micro-Array Based Immunoassay by Direct NIR Fluorescence and Quantitative Image Analysis | p. 65 |
| Biology Lab-on-a-Chip for Drug Screening | p. 69 |
| Results Obtained Using a Prototype Microfluidics-Based Hematology Analyzer | p. 73 |
| Rare Event Cell Sorting in a Microfluidic System for Application in Prenatal Diagnosis | p. 77 |
| Simultaneous Self-Referencing Analyte Determination in Complex Sample Solutions using Microfabricated Flow Structures (T-Sensors) | p. 81 |
| Fabrication of Injection and Switching Micro Valve for Whole Blood Control | p. 85 |
| A Microfluidics-Based Microcytometer: Interfacing Microfluidics with Macrofluidics | p. 89 |
| Microfabricated Biosensors for Measuring Neurotransmitters from Cultured Nerve Cells | p. 93 |
| Anti-Resonant Reflecting Optical Waveguides (ARROWS) as Optimal Optical Detectors for [mu]TAS Applications | p. 97 |
| Probe Beam Deflection of Isotachophoresis on Miniaturised Planar Glass Devices | p. 101 |
| Integration of Microelectrodes with Etched Microchannels for In-Stream Electrochemical Analysis | p. 105 |
| On-line Detection of Electrophoretic Separations on a Microchip by Raman Spectroscopy | p. 109 |
| Electrophoretic Separations in Ultrathin Channels Using Microelectrode Array Detection | p. 113 |
| Micromechanical Thermogravimetry on Single Zeolite Crystals | p. 117 |
| A One-Spot Electrochemical Transducer for use in [mu]TAS | p. 121 |
| Various Current Regimes Applicable for Sensing in [mu]TAS | p. 125 |
| Optimization of a Porous Silicon Carrier Matrices Applied in Chip Based Micro-Enzyme Reactors | p. 129 |
| Electrochemical Fabrication of Multi Walled Micro Channels | p. 133 |
| Utilizing the {lll} Plane Switch-Over Etching Process for Micro Fluid Control Applications | p. 137 |
| Coupling Electrospray Mass Spectrometry to Microfluidic Devices with Low Dead Volume Connections | p. 141 |
| Silicon-Micromachined Separation Columns Coated with Amino Acid Films for an Integrated On-chip Gas Chromatograph | p. 145 |
| Computer Simulations for Microchip Electrophoresis | p. 149 |
| Electrophoretic Separation of Antisense DNA using Polymer-solution filled Capillary by Cross-Injection | p. 153 |
| Integrated Serial Dilution on a Microchip for Immunoassay Sample Treatment and Flow Injection Analysis | p. 157 |
| Minimizing Dispersion Introduced by Turns on Microchips | p. 161 |
| Use of Surfactant Additives for Modification of Electroosmotic Flow and Wall Chemistry | p. 165 |
| Sample Matrix Effects on Injection and Sample Loading in Integrated Capillary Electrophoresis Devices | p. 169 |
| Development of a Microfabricated Biochemical Workbench - Improving the Mixing Efficiency | p. 173 |
| Micro Mixer Incorporated with Piezoelectrically Driven Valveless Micropump | p. 177 |
| Liquid Mixing Studies with an Integrated Mixer/Valve | p. 181 |
| Fabrication of an Integrated Mixing/Reaction Micro Flow Cell for [mu]-TAS | p. 185 |
| Micro-fluidic Diffusion Coefficient Measurement | p. 189 |
| Sizing, Fractionation and Mixing of Biological Objects via Microfabricated Devices | p. 193 |
| Individual Embryo Transport and Retention on a Chip | p. 199 |
| Single Cell Enzymatic Analysis on a Microchip: Lysing of Single Cells and Identification of their [beta]-Galactosidase Activity | p. 203 |
| Applying Microfluidic Chemical Analytical Systems to Imperfect Samples | p. 207 |
| Building Highly Diverse Arrayed Substance Libraries by Micro Offset Printing | p. 213 |
| Fluorescence Array Biosensor - Biochemistry and Application | p. 217 |
| An Integrated Microelectronic Hybridization System for Genomic Research and Diagnostic Applications | p. 221 |
| Development of a Generic Microfluidic System for Electrochemical Immunoassay-Based Remote Bio/Chemical Sensors | p. 225 |
| Integrated Microsystem for Sample Introduction, Mixing, Reaction, Separation and Self Calibration of Immunoassays | p. 231 |
| Continuous-flow vs. Batch Process - a Few Examples | p. 235 |
| Micro-TAS on Polymer Substrates Micromachined by Laser Photoablation | p. 241 |
| Key Elements of a Transparent Teflon Microfluidic System | p. 245 |
| An Inexpensive Plastic Technology for Microfabricated Capillary Electrophoresis Chips | p. 249 |
| Microfluidic Manifolds by Polymer Hot Embossing for [mu]-TAS Applications | p. 253 |
| Multiplexed, Disposable, Plastic Microfluidic Systems for High-Throughput Applications | p. 257 |
| Micro-Genetic Analysis Systems | p. 261 |
| A Microfabricated Fluidic Reaction and Separation System for Integrated DNA Analysis | p. 267 |
| High Performance DNA Separations in Microchip Electrophoresis Systems | p. 271 |
| Nucleic Acid Concentration and PCR for Diagnostic Applications | p. 277 |
| Microoptical Fluorescence Detection for Chip-Based Multiplexed Analysis Systems | p. 281 |
| Micro-Optical Systems for Fluorescence Detection in [mu]-TAS Applications | p. 287 |
| Integrated Bio/Chemical Microsystems Employing Optical Detection: A Cytometer | p. 291 |
| Photothermal Ultrasensitive Detection and Microchemistry in the Integrated Chemistry Lab | p. 295 |
| Impedances for Design of Microfluidic Systems | p. 299 |
| Miniaturized Electrocaloric Flow Controller for Analyte Muliplexing and Cell/Particle Sorting | p. 303 |
| Hydrophobic Microcapillary Vent for Pneumatic Manipulation of Liquid in [mu]-TAS | p. 307 |
| Microfabricated Chips for Capillary Electrophoresis on Quartz Glass Substrates Using a Bonding with Hydrofluoric Acid | p. 311 |
| Rapid Electrophoretic and Chromatographic Analysis on Microchips | p. 315 |
| Free Flow Electrophoresis Module Fabricated with Pyrex Glass | p. 319 |
| A Miniaturized Planar Isotachophoresis Separation Device for Transition Metals with Integrated Conductivity Detection | p. 323 |
| Characterization of Silicon-Based Insulated Channels for Capillary Electrophoresis | p. 327 |
| Novel Microfabricated Capillary Array Electrophoresis Chip Fabricated by Synchrotron Radiation and Direct Observation of Dynamics of DNA Molecules Migrating in Microchannels | p. 331 |
| Continuous Flow versus Stopped Flow in a Micro Flow Injection System | p. 335 |
| Microfabricated Channels and Fluid Control Systems for Integrated Flow Injection Analysis | p. 339 |
| Microfabricated Dual-Microdialysis and Capillary Isoelectric focusing Devices for Cleanup and Separations/ Mass Spectrometric Analysis of Biomolecules | p. 343 |
| Chip-based Heterogeneous Immunoassay for Clinical Diagnostic Applications | p. 347 |
| Micro-Analytical ([mu]FIA) Reactor for the Determination of Phosphate as Orthophosphate | p. 351 |
| Investigation of Chemiluminescent MicroAnalytical Systems | p. 355 |
| Isotachophoresis on Planar Polymeric Substrates | p. 359 |
| Application of Thin Cross-Linked Gelatin Layers in Micro Systems Technology | p. 363 |
| Plastic Microfluid Devices for Clinical Measurements | p. 367 |
| Fabrication Processes for Polymer-based Microfluidic Analytical Devices | p. 371 |
| [mu]-Structured Polymers as Components of Chemical Microreactors | p. 375 |
| Development of Microfabricated Valves for [mu]TAS | p. 379 |
| A Silicon Micropump with a High Bubble Tolerance and Self-Priming Capability | p. 383 |
| Flow-through Microdispensing: Design and Applications | p. 387 |
| Manufacturing of Self-Priming Plastic Micropumps | p. 391 |
| Micromachined Bi-directional Liquid Pump with Thermally Controlled Dynamic Valves | p. 395 |
| Micro Ball Valve for Fluidic Micropumps and Gases | p. 399 |
| Nanomanipulation Techniques Inside the SEM - First Attempts to Integrate Microfabrication into a SEM | p. 403 |
| Fluidics for a Multi-analyte Detector Based on Intermolecular Binding Forces | p. 407 |
| Reagent Handling by Manipulation of Magnetic Particles: A New Approach to the Automation and Miniaturization of Analytical Chemistry | p. 411 |
| Novel DNA Manipulation Based on Local Temperature Control: Transportation and Scission | p. 415 |
| Numerical Simulation of Magnetic Separation of Particles in a Rectangular Microchannel | p. 419 |
| Automated Microchip Platform for Biochemical Analysis | p. 423 |
| Automatic Sensor System for Water Analysis | p. 427 |
| Fluorescence Array Biosensor - Part I: Optics and Fluidics | p. 431 |
| Microseparations and Microfluidic Studies | p. 435 |
| [mu]TAS for Volumetric or Coulometric Titrations of Nanomole Amounts of Analytes in Microliter Samples | p. 439 |
| System Requirements for a Portable Cell Based Sensor | p. 443 |
| Laboratory on Chip for Clinical Applications | p. 447 |
| Microfabricated Liquid Chromatography Columns Based on Collocated Monolith Support Structures | p. 451 |
| Towards a Modular Microfluidic System for Proteome Analysis by Mass Spectrometry | p. 457 |
| Integrated Gas Phase Microreactors | p. 463 |
| In Situ Detection of Cells and Biochemical Reactions by Optical Diffraction | p. 469 |
| Micromachined Flame Analysers (Atomic Emission Flame Spectrometer (AES) Flame Ionization Detector (FID)) | p. 473 |
| Integrated Chemical Analysis Systems for Gas Phase CW Agent Detection | p. 477 |
| Authors index | p. 483 |
| Subject index | p. 489 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
ISBN: 9780792353225
ISBN-10: 0792353226
Published: 30th September 1998
Format: Hardcover
Language: English
Number of Pages: 512
Audience: General Adult
Publisher: Springer Nature B.V.
Country of Publication: NL
Dimensions (cm): 22.23 x 15.88 x 2.54
Weight (kg): 0.89
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