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Methods for Genetic Risk Assessment - David Brusick

Methods for Genetic Risk Assessment

By: David Brusick

Hardcover | 11 January 1994 | Edition Number 1

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Genetic disease contributes to a major portion of our health care costs. While most of the human genetic burden is transmitted from generation to generation, environmental chemicals capable of reacting with germ cell DNA could produce new mutations, resulting in an even greater genetic liability for the next generation. The potential impact of environmental mutagens on the health and viability of other living things is important to consider as well. "Methods for Genetic Risk Assessment" features contributions from international experts to provide a comprehensive review of the current status of genetic risk assessment. This book covers various methods and strategies for conducting genetic risk assessments on human populations, as well as when and how to conduct them. The potential effects of environmental genotoxins on non-human organisms are also examined. Topics considered include: Genetic hazard identification; Genetic risk characterization; Exposure assessment; Dose-response kinetics; Methods for environmental monitoring for genotoxicity; Assessment options and risk management.

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