
Hemodynamical Flows
Modeling, Analysis and Simulation
By: Giovanni P. Galdi, Rolf Rannacher, Anne M. Robertson
Paperback | 18 March 2008
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516 Pages
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This book surveys a broad range of research results on the physical and mathematical modeling, as well as the numerical simulation of hemodynamical flows, that is, of the complex fluid and structural mechanical processes that occur in the human blood circulation system. The topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; mesh and mode adaptivity; particle transport in channels and pipes; artificial boundary conditions, and many more. Hemodynamics is an area of active current research, and this book provides an entry into the field for graduate students and researchers. Hemodynamical Flows was developed out of a series of lectures presented by the authors at the Oberwolfach Research Institute (MFO) in Oberwolfach-Walke, Germany, in November, 2005.
Industry Reviews
From the reviews:
"This volume consists of six contributions concerning mathematical tools and analysis for the blood flow in arteries and veins. ... book will be handy for those who are interested in the description of the flows of fluids with unusual properties, especially, of course, blood. It is suitable for physicists, mathematicians working in the analysis of fluid flows, students specializing in the mathematical modelling of fluids, and other related specialists. Libraries of technical and natural sciences universities are strongly recommended to provide this well written collection." (Ivan Straskraba, Applications of Mathematics, Vol. 56 (6), 2011)| Preface | p. x |
| Review of Relevant Continuum Mechanics | p. 1 |
| Kinematics | p. 3 |
| Description of motion of material points in a body | p. 3 |
| Referential and spatial descriptions | p. 4 |
| Deformation gradient and measures of stretch and strain | p. 5 |
| Velocity gradient and the rate of deformation tensor | p. 7 |
| Special motions | p. 8 |
| Governing equations | p. 9 |
| The transport theorem | p. 9 |
| Conservation of mass | p. 10 |
| Balance of linear momentum | p. 11 |
| Balance of angular momentum | p. 13 |
| Mechanical energy equation | p. 14 |
| Balance of energy | p. 14 |
| Restrictions on constitutive equations | p. 15 |
| Nonlinear viscous fluids | p. 18 |
| Restrictions due to invariance requirements | p. 19 |
| Restrictions on the Reiner-Rivlin equation due to behavior of real fluids | p. 19 |
| Restrictions on generalized Newtonian fluids due to thermodynamic considerations | p. 20 |
| Examples of generalized Newtonian fluids | p. 20 |
| Yield stress "fluids" | p. 21 |
| Bingham model | p. 22 |
| Modified Bingham model | p. 24 |
| Herschel-Bulkley model | p. 24 |
| Casson model | p. 25 |
| Viscoelastic fluids | p. 25 |
| Simple fluids | p. 26 |
| Approximations for simple fluids with fading memory | p. 31 |
| Finite viscoelastic models | p. 34 |
| Thixotropic fluids | p. 36 |
| Rheometrical flows | p. 38 |
| Viscometric flows | p. 38 |
| Periodic flows | p. 45 |
| Non-periodic unsteady flows | p. 51 |
| Rheometers | p. 53 |
| Couette rheometer | p. 54 |
| Cone and plate rheometer | p. 54 |
| Capillary rheometer | p. 55 |
| Nonlinear elastic solids | p. 55 |
| Introduction to hyperelastic materials | p. 56 |
| Invariance restrictions | p. 57 |
| Example: incompressible, isotropic hyperelastic materials | p. 58 |
| References | p. 59 |
| Hemorheology | p. 63 |
| Blood components | p. 66 |
| Plasma | p. 67 |
| Red blood cells (Erythrocytes) | p. 67 |
| White blood cells (Leukocytes) | p. 68 |
| Platelets (Thrombocytes) | p. 69 |
| Relevant parameters for flow in the human cardiovascular system | p. 69 |
| Multiphase behavior of blood in shear flows | p. 72 |
| Low shear behavior: aggregation and disaggregation of erythrocytes | p. 73 |
| High shear rate behavior: deformation, tumbling and realignment of erythrocytes | p. 75 |
| Spatial distribution of erythrocytes in shear flows | p. 76 |
| Outcomes of non-homogeneous distribution of erythrocytes | p. 77 |
| Platelet activation and blood coagulation | p. 78 |
| Vasoconstriction | p. 78 |
| Primary hemostasis | p. 78 |
| Secondary hemostasis or clot formation | p. 79 |
| Wall repair and clot dissolution | p. 79 |
| Models of activation and blood coagulation | p. 79 |
| Special considerations in rheometry of blood | p. 80 |
| Inhomogeneous distribution of particles | p. 80 |
| Thixotropy | p. 82 |
| Biochemical effects | p. 82 |
| Other considerations | p. 82 |
| Viscosity of whole blood | p. 83 |
| Nomenclature for blood viscosity | p. 83 |
| Experimental data for whole blood viscosity | p. 84 |
| Significance of shear thinning in the circulatory system | p. 86 |
| Viscosity models for blood | p. 89 |
| Dependence of blood viscosity on factors other than shear rate | p. 90 |
| Yield stress behavior of blood | p. 96 |
| Yield stress data for blood | p. 97 |
| Yield stress constitutive models for blood | p. 99 |
| Viscoelasticity of blood | p. 100 |
| Measurements of blood viscoelasticity | p. 100 |
| Dependence of viscoelasticity on other factors | p. 105 |
| Significance of viscoelasticity in the circulatory system | p. 107 |
| Viscoelastic constitutive models | p. 107 |
| Disease states and mechanical properties of blood | p. 108 |
| Increased hematocrit | p. 108 |
| Plasma hyperviscosity | p. 109 |
| Hyperaggregation of red blood cells | p. 109 |
| Decreased RBC deformability | p. 109 |
| Gender and the mechanical properties of blood | p. 110 |
| References | p. 112 |
| Mathematical Problems in Classical and Non-Newtonian Fluid Mechanics | p. 121 |
| Problems in the pipe flow of a Navier-Stokes liquid | p. 125 |
| Fully developed flows | p. 125 |
| The entry flow problem | p. 142 |
| Mathematical modeling of a piping system. Unbounded domain approach | p. 148 |
| Mathematical modeling of a piping system. Bounded domain approach with "do-nothing" boundary conditions | p. 171 |
| Problems in non-Newtonian fluid mechanics | p. 193 |
| Why non-Newtonian models? | p. 193 |
| Problems related to generalized Newtonian models | p. 196 |
| Problems related to viscoelastic liquid models | p. 220 |
| Some results in the mathematical theory of second-order fluids 226 | |
| Some results in the mathematical theory of Oldroyd-B fluids and related models | p. 232 |
| Problems in liquid-particle interaction | p. 236 |
| Sedimentation of symmetric particles in viscoelastic liquid | p. 238 |
| Shape-tilting phenomenon | p. 245 |
| Motion of a disk in the shear flow of a liquid in a horizontal channel | p. 247 |
| References | p. 266 |
| Methods for Numerical Flow Simulation | p. 275 |
| Finite-element methods for the simulation of viscous flow | p. 276 |
| The Navier-Stokes equations | p. 276 |
| Discretization of space | p. 278 |
| The stationary algebraic problems | p. 284 |
| Discretization of time | p. 284 |
| The quasi-stationary algebraic problems | p. 288 |
| Numerical simulation of pipe flow | p. 289 |
| Variational `open' boundary conditions | p. 289 |
| Problems with the `do-nothing' boundary condition | p. 292 |
| The problem of well-posedness | p. 293 |
| The closure problem | p. 294 |
| Mesh adaptation and model calibration | p. 295 |
| Principles of a-posteriori error estimation | p. 296 |
| The dual weighted residual (DWR) method | p. 298 |
| Model problems and practical aspects | p. 304 |
| Hyperbolic model case: transport problem | p. 310 |
| Application to flow models | p. 315 |
| Application in optimal flow control | p. 320 |
| Application in hydrodynamic stability analysis | p. 321 |
| Calibration of flow models | p. 323 |
| Current work and further development | p. 328 |
| References | p. 328 |
| Numerics of Fluid-Structure Interaction | p. 333 |
| Fluid-`single rigid body' interaction | p. 334 |
| Model setup in the body frame | p. 335 |
| The stationary free-fall problem | p. 337 |
| Numerical approximation | p. 339 |
| The issue of domain truncation | p. 343 |
| Toward economical meshes | p. 344 |
| Hydrodynamic stability | p. 350 |
| Dynamics of non-stationary free fall | p. 350 |
| Open problems and further development | p. 351 |
| Fluid-`many rigid bodies-wall' interaction | p. 352 |
| The stress-DLM method | p. 352 |
| The fractional-step scheme | p. 353 |
| Open problems and further development | p. 356 |
| Fluid-`elastic structure' interaction | p. 357 |
| Solution methods for FSI problems | p. 357 |
| Variational formulation | p. 358 |
| Numerical approximation | p. 363 |
| Mesh adaptation | p. 365 |
| Stationary test case `Elastic Flow Cavity' | p. 369 |
| Non-stationary test case `Vibrating Thin Plate' | p. 371 |
| Open problems and further development | p. 373 |
| References | p. 375 |
| Numerical Techniques for Multiphase Flow with Liquid-Solid Interaction | p. 379 |
| Numerical methods for incompressible flow | p. 380 |
| Introduction | p. 380 |
| Discretization of the Navier-Stokes equations in time | p. 382 |
| Discretization of the Navier-Stokes equations in space | p. 387 |
| Pressure Schur complement solvers | p. 394 |
| Global MPSC approach | p. 397 |
| Local MPSC approach | p. 401 |
| Multilevel solution strategy | p. 403 |
| Coupling with scalar equations | p. 405 |
| Coupling with k - ¿ turbulence model | p. 408 |
| Adaptive time-step control | p. 413 |
| Some numerical examples | p. 415 |
| Application to more complex flow models | p. 418 |
| Conclusions | p. 429 |
| FSI for fluid - elastic solid configurations | p. 431 |
| Overview | p. 431 |
| Continuum description | p. 433 |
| Fluid structure interaction problem formulation | p. 438 |
| Applications | p. 447 |
| FSI benchmark | p. 451 |
| Conclusion | p. 454 |
| Numerical techniques for fluid-rigid solid configurations | p. 457 |
| Introduction | p. 457 |
| Description of the physical models | p. 460 |
| Moving-mesh method | p. 462 |
| Numerical method | p. 464 |
| Numerical results | p. 471 |
| Conclusions | p. 485 |
| References | p. 492 |
| Table of Contents provided by Publisher. All Rights Reserved. |
ISBN: 9783764378059
ISBN-10: 3764378050
Series: Oberwolf Seminars
Published: 18th March 2008
Format: Paperback
Language: English
Number of Pages: 516
Audience: Professional and Scholarly
Publisher: Springer Nature B.V.
Country of Publication: CH
Dimensions (cm): 24.13 x 16.51 x 3.18
Weight (kg): 1.0
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