Heart Function and Metabolism

A. Special Lecture.- 1. Molecular Biology and Cardiac Function, Past, Present and Future.- B. Electrical Events and Ions.- 2. Regulation of Calcium Slow Channels and Potassium Channels of Cardiac Muscle by Cyclic Nucleotides and Metabolism.- 3. Potassium Channels Identified with Single Channel Recordings and Their Role in Cardiac Excitation.- 4. Na and Ca Channels in the Heart.- 5. Sodium Pathways In and Out of the Cardiac Cells: Relationship to Inotropy.- 6. Nondriven Electrical Activity in Cardiac Ventricular Fibers.- 7. Regulation of Cl? Activity in Ventricular Muscle: Cl?/HCO?3 Exchange and Na+ - dependent Cl? Cotransport.- C. Sarcolemmal Functions.- 8. Parasympathetic Control of the Heart: Subcellular Mechanisms.- 9. Role of Phosphatidylethanolamine N-Methylation on Ca2+ Transport in Cardiac Membranes.- 10. Na+ - Ca2+ Exchange in Cardiac Sarcolemmal Vesicles.- 11. Na/K Pump Function in Cultured Embryonic Chick Heart Cells.- 12. Characteristics of Ca2+/Mg2+ ATPase in Heart Sarcolemma Treated with Trypsin.- D. Sarcoplasmic Reticulum Function.- 13. Depression of Canine Ventricular Sarcoplasmic Reticulum by the Calcium Channel Agonist, Bay K 8644.- 14. Biophysical Aspects of Ca2+ - Transport Sites in Skeletal and Cardiac Sarcoplasmic Reticulum (Ca2+ + Mg2+)-ATPase.- 15. Mechanisms of Sarcoplasmic Reticulum Functions and Consequences for Muscle Activity.- 16. Protein Phosphorylation in Cardiac Sarcoplasmic Reticulum and Its Functional Consequences.- 17. The Ca2+ ATPase of Cardiac Muscle Sarcoplasmic Reticulum.- E. Contractile Protein Functions.- 18. Contractile and Regulatory Proteins in Cardiovascular System.- 19. Distribution of Cardiac Myosin Isozymes in Human and Rat Heart-Immunohistochemical Study Using Monoclonal Antibodies.- 20. Remodelling of the Myocyte at a Molecular Level - Relationship Between Myosin Isoenzyme Population and Sarcoplasmic Reticulum.- 21. Isomyosins and Isoactins in Mammalian Myocardium.- 22. Crossbridge Mechanisms of Contraction in Vascular Smooth Muscle.- F. Functional Aspect of Metabolism.- 23. Control of Glucose Uptake and Utilization in the Myocardium.- 24. Blockade of Sugar Transport Decreases Contractility of Aortic Smooth Muscle.- 25. Control of Energy Transport in Cardiac Muscle. Dissociation of ATP Levels from Contractile Function; Cardiac Failure Due to Phosphocreatine Deficiency.- 26. Creatine Kinase and Mechanical Properties of Rat Ventricular Muscle.- 27. Hemodynamic Performance of Creatine-Depleted Rat Heart in Isolated Blood-Perfused Working Preparation.- 28. Localization of Glucose-6-Phosphatase (G-6-Pase) in the Rat Heart Muscle Cells.