Genetic Polymorphism and Disease

Name: Genetic Polymorphism and Disease
Brand: Taylor & Francis Ltd
Price: 324.75 AUD
Availability: BackOrder

By: Syed Sameer Aga (Editor), Mujeeb Zafar Banday (Editor), Saniya Nissar (Editor)

Write A Review

Hardcover | 6 December 2022 | Edition Number 1

At a Glance

Hardcover
540 Pages

Dimensions(cm)
28.0 x 21.0 x 3.18

Hardcover

RRP $378.00

$324.75

14%OFF

or 4 interest-free payments of $81.19 with

or

Available for Backorder. We will order this from our supplier however there isn't a current ETA.

Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins.

Key Features

Describes the genetic polymorphism and its various types
Discusses the role of genetic polymorphisms in modulating the risk of various human diseases
Explores various molecular techniques used for detecting GPs
Characterizes the role of SNPs in modulating the susceptibility of human diseases
Provides a genetic basis for individual variations in response to therapeutics

Industry Reviews

This book will be useful to researchers interested in one of the diseases described and those who are new to studying the relationship between a particular disease and inherited variation...[and] is a welcome addition to the currently available literature."

- Mark F. Sanders, PhD (UC Davis College of Biological Sciences)

Shipping

	Standard Shipping	Express Shipping
Metro postcodes:	$9.99	$14.95
Regional postcodes:	$9.99	$14.95
Rural postcodes:	$9.99	$14.95

Orders over $79.00 qualify for free shipping.

How to return your order

At Booktopia, we offer hassle-free returns in accordance with our returns policy. If you wish to return an item, please get in touch with Booktopia Customer Care.

Additional postage charges may be applicable.