| List of principal contributors | p. ix |
| Preface | p. xii |
| Setting the Scene: Epidemiology | |
| Epidemiology of functional bowel disease and inflammatory bowel disease: a common link? | p. 3 |
| Extraintestinal manifestations and psychiatric illness in irritable bowel syndrome: is there a link? | p. 10 |
| Evidence of bidirectional cross-sensitization of the distal colon and lower urinary tract: a possible aetiology of concurrent irritable bowel syndrome and interstitial cystitis | p. 17 |
| Are dissociative mental disturbances responsible for visceral hyperalgesia in patients with functional abdominal pain? | p. 29 |
| Basic Mechanisms of Gastrointestinal Inflammation | |
| Current knowledge regarding the initiation and regulation of gastrointestinal inflammation in inflammatory bowel disease | p. 35 |
| Is the normal gut inflamed? And does it matter? | p. 44 |
| Disturbed Function in Inflammatory Bowel Disease | |
| Symptomatic inflammatory bowel disease in remission--it could be irritable bowel syndrome | p. 53 |
| The symptomatic IBD patient in remission--a manifestation of IBS?--Cons | p. 57 |
| Herbal preparation in functional dyspepsia--Helicobacter pylori status is not a predictor for treatment success: results of a double-blind, randomized, placebo-controlled, multicentre trial | p. 62 |
| Intestinal gas dynamics and tolerance are modified by the different components of nutrients | p. 70 |
| Inflammation and Nerve Function | |
| Vagal afferents and regulation of inflammation and hyperalgesia in remote body domains | p. 79 |
| Inflammation-induced changes in nerves as a basis for symptom generation in irritable bowel syndrome | p. 104 |
| Inflammation-induced altered nerve function in the gut-does it play a role in gastrointestinal symptom generation? | p. 109 |
| Colonic spinal primary afferents: mechanosensory and chemosensory subtypes and effects of inflammation | p. 120 |
| Regulation of vagal afferent sensitivity to gastric acid | p. 126 |
| Alterations of the enteric nervous system and interstitial cells of Cajal in functional colorectal motility disorders | p. 136 |
| Nerve Function Modulating Gut Inflammation | |
| Sensory nerve function in gut inflammation | p. 151 |
| Neuroimmunology and the gastrointestinal tract | p. 160 |
| What Function is Disturbed in Functional Gastrointestinal Disorders and Why? | |
| Visceral hypersensitivity in functional gastrointestinal disorders | p. 169 |
| Motor function and dysfunction in functional dyspepsia and irritable bowel syndrome | p. 176 |
| A rational approach to Helicobacter pylori eradication in patients with functional dyspepsia | p. 187 |
| Con: Helicobacter pylori eradication--a rational approach for the treatment of patients with functional dyspepsia? | p. 196 |
| Animal Models on the Role of Inflammation in Gastrointestinal Function | |
| Animal models for visceral sensitivity | p. 205 |
| Descending modulation of visceral hyperalgesia | p. 213 |
| Role of Acute Bacterial Infections in Irritable Bowel Syndrome | |
| Epidemiology and clinical impact of post-infectious irritable bowel syndrome | p. 223 |
| Potential mechanisms and therapeutic implications of bacterial infection in irritable bowel syndrome | p. 229 |
| Role of epithelium--environment interactions in down-regulation of mucosal inflammation | p. 239 |
| Genetics and Molecular Mechanisms | |
| Is irritable bowel syndrome a genetic disorder? | p. 245 |
| Localization and functions of neurokinin and N-methyl-D-aspartate receptors | p. 253 |
| Replacing physiological variability by genetic variability--from gene to function | p. 260 |
| The Brain, the Gut and the Genes | |
| Gut function and dysfunction in functional gastrointestinal disorders: a personal view | p. 269 |
| Index | p. 277 |
| Table of Contents provided by Ingram. All Rights Reserved. |
